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CYBB gene

Known as: GP91-1, p91-PHOX, NADPH OXIDASE 2 
This gene plays a role in the generation of superoxide in phagocytes.
National Institutes of Health

Related topics

Related topics

7 relations
Acid-Base EquilibriumAntigen ProcessingCYBB protein, humanCell Respiration

Papers overview

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2019
2019
miR‐141 alleviates LPS‐induced inflammation injury in WI‐38 fibroblasts by up‐regulation of NOX2
Review
2014
Review
2014
Platelet NOX, a novel target for anti-thrombotic treatment
Summary There is a growing body of evidence to suggest that reactive oxidant species (ROS) including O2 −, OH− or H2O2 act as… 
2012
2012
Decreased STAT5 phosphorylation and GATA‐3 expression in NOX2‐deficient T cells: Role in T helper development
Absence of phagocyte NADPH oxidase (NOX2) activity causes chronic granulomatous disease (CGD), a primary immunodeficiency… 
Highly Cited
2008
Highly Cited
2008
Nox4 Oxidase Overexpression Specifically Decreases Endogenous Nox4 mRNA and Inhibits Angiotensin II–Induced Adventitial Myofibroblast Migration
The vascular adventitia is emerging as an important modulator of vessel remodeling. Adventitial myofibroblasts migrate to the… 
Highly Cited
2007
Highly Cited
2007
HIV-1 Tat Activates Dual Nox Pathways Leading to Independent Activation of ERK and JNK MAP Kinases*
Human immunodeficiency virus, type 1 Tat is known to exert pleiotropic effects on the vascular endothelium through mitogen… 
2001
2001
Improved superoxide-generating ability by interferon gamma due to splicing pattern change of transcripts in neutrophils from patients with a splice site mutation in CYBB gene.
Chronic granulomatous disease (CGD) is an inherited disorder of host defense against microbial infections caused by defective… 
Highly Cited
1999
Highly Cited
1999
Differentiation of Serpulina species by NADH oxidase gene (nox) sequence comparisons and nox-based polymerase chain reaction tests.
1996
1996
Detection of gp91-phox precursor protein in B-cell lines from patients with X-linked chronic granulomatous disease as an indicator for mutations impairing cytochrome b558 biosynthesis.
NADPH oxidase cytochrome b558 consists of two subunits, gp91-phox and p22-phox, defects of which result in chronic granulomatous… 
1993
1993
X-linked chronic granulomatous disease: correction of NADPH oxidase defect by retrovirus-mediated expression of gp91-phox.
Chronic granulomatous disease (CGD) is an inherited immunodeficiency resulting from the inability of an individual's phagocytes… 
1992
1992
Evidence for the involvement of distinct signal transduction pathways in the regulation of constitutive and interferon gamma-dependent gene expression of NADPH oxidase components (gp91-phox, p47-phox…
We recently showed that mRNA levels coding the high-affinity Fc gamma receptor for IgG (Fc gamma R-I, CD64) and two of the… 
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