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In-feed antibiotic effects on the swine intestinal microbiome
Analysis of the metagenomes showed that microbial functional genes relating to energy production and conversion were increased in the antibiotic-fed pigs and that antibiotic resistance genes increased in abundance and diversity in the medicated swine microbiome despite a high background of resistance genes in nonmedication swine.
Phylogenetic analysis of the spirochetes
This study represents the first demonstration that pathogenic and saprophytic Leptospira species are phylogenetically related and supported the conclusion that the spirochetes represent a monophylectic bacterial phylum.
Recognition of two new species of intestinal spirochetes: Serpulina intermedia sp. nov. and Serpulina murdochii sp. nov.
On the basis of DNA-DNA hybridization data, nine intestinal spirochete strains were grouped into five genospecies and new Serpulina species were found, for which the names SerPulina intermedia sp.
Serpulina pilosicoli sp. nov., the agent of porcine intestinal spirochetosis.
DNA-DNA relative reassociation experiments in which the S1 nuclease method was used revealed that intestinal spirochete strain P43/6/78T was related to, but was genetically distinct from, both S. hyodysenteriae B78T and S. innocens B256T, and it is proposed that strain P 43/ 6/78 should be designated as the type strain of a new species, Serpulina pilosicoli.
Bacteria, phages and pigs: the effects of in-feed antibiotics on the microbiome at different gut locations
The collateral effects on the microbiota of antibiotic-fed animals caused divergence from that of control animals, with notable changes being increases in Escherichia coli populations in the ileum, Lachnobacterium spp.
Proposal to change the genus designation Serpula to Serpulina gen. nov. containing the species Serpulina hyodysenteriae comb. nov. and Serpulina innocens comb. nov.
  • T. Stanton
  • Biology
    International journal of systematic bacteriology
  • 1992
The bacterial genus Serpula Stanton et al. 1991 is illegitimate due to the existence of a fungal genus Serpula Pers. ex S. F. Gray. Consequently, a new genus designation, Serpulina, is proposed for
Antibiotics in Feed Induce Prophages in Swine Fecal Microbiomes
Comparative metagenomics shows that prophages are induced by in-feed antibiotics in swine fecal microbiomes and that antibiotic resistance genes were detected in most viromes, suggesting that in- feed antibiotics are contributing to phage-mediated gene transfer, potentially of antibiotic resistant genes, in the swine gut.
Purification and characterization of VSH-1, a generalized transducing bacteriophage of Serpulina hyodysenteriae
Findings indicate that induced VSH-1 virions package DNA of S. hyodysenteriae are capable of transferring host genes between cells of that spirochete and are incapable of lytic growth on any of five intestinal spiroChete strains.
Proposal of Roseburia faecis sp. nov., Roseburia hominis sp. nov. and Roseburia inulinivorans sp. nov., based on isolates from human faeces.
Seven recently cultured bacterial isolates, although similar in their 16S rRNA gene sequences to Roseburia intestinalis L1-82(T) (DSM 14610(T)), were not sufficiently related for inclusion within