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CXCR4 gene

Known as: NPYY3R, LIPOPOLYSACCHARIDE-ASSOCIATED PROTEIN 3, HSY3RR 
This gene is involved in the mediation of viral entry into cells and cellular migration and chemotaxis.
National Institutes of Health

Related topics

Related topics

18 relations
Acquired Immunodeficiency SyndromeApoptosisCXCR4 ReceptorsCXCR4 WHIM-Like Mutation

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CXCR4 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Targeting CXC motif chemokine receptor 4 inhibits the proliferation, migration and angiogenesis of lung cancer cells.
An increasing volume of data indicates that disrupting the interaction between CXC motif chemokine receptor 4 (CXCR4) and its… 
2016
2016
Increased HIV-1 sensitivity to neutralizing antibodies by mutations in the Env V3-coding region for resistance to CXCR4 antagonists.
HIV-1 passage in cell culture in the presence of chemokine receptor antagonists can result in selection of viruses with env… 
2015
2015
HIV-1 Coreceptor CXCR4 Antagonists Promote Clonal Expansion of Viral Epitope-Specific CD8+ T Cells During Acute SIV Infection in Rhesus Monkeys In Vivo
Background: The underlying molecular mechanisms and the kinetics of T cell receptor (TCR) repertoire selection during… 
2013
2013
Silencing of CXCR4 Inhibits Tumor Cell Proliferation and Neural Invasion in Human Hilar Cholangiocarcinoma
Background/Aims To evaluate the expression of CXC motif chemokine receptor 4 (CXCR4) in the tissues of patients with hilar… 
2013
2013
Occurrence and fate of N-nitrosamines and their formation potential in three wastewater treatment plants in Japan.
N-nitrosamines are well known as carcinogens present in the environment. However, studies of the occurrence and fate of N… 
2005
2005
Complex Determinants in Human Immunodeficiency Virus Type 1 Envelope gp120 Mediate CXCR4-Dependent Infection of Macrophages
ABSTRACT Host cell range, or tropism, combined with coreceptor usage defines viral phenotypes as macrophage tropic using CCR5 (M… 
2003
2003
Solid state and solution conformation of 2-pyridinecarboxylic acid hydrazides: a new structural motif for foldamers
2002
2002
Neuropathogenesis of lentiviral infection in macaques: roles of CXCR4 and CCR5 viruses and interleukin-4 in enhancing monocyte chemoattractant protein-1 production in macrophages.
2001
2001
HIV envelope proteins differentially utilize CXCR4 and CCR5 coreceptors for induction of apoptosis.
The involvement of CXCR4 and CCR5 coreceptors in apoptosis induced by the HIV envelope (Env) proteins has not been well defined… 
Highly Cited
2000
Highly Cited
2000
Coreceptor Competition for Association with CD4 May Change the Susceptibility of Human Cells to Infection with T-Tropic and Macrophagetropic Isolates of Human Immunodeficiency Virus Type 1
ABSTRACT The chemokine receptors CCR5 and CXCR4 were found to function in vivo as the principal coreceptors for M-tropic and T… 
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