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CXCR4 gene

Known as: NPYY3R, LIPOPOLYSACCHARIDE-ASSOCIATED PROTEIN 3, HSY3RR 
This gene is involved in the mediation of viral entry into cells and cellular migration and chemotaxis.
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
Two novel stem cell factor (SCF) dependent human mast cell lines, designated LAD 1 and 2, were established from bone marrow… Expand
Highly Cited
2003
Highly Cited
2003
Small-cell lung cancer (SCLC) is an aggressive, rapidly metastasizing neoplasm. The chemokine stromal cell-derived factor-1 (SDF… Expand
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Highly Cited
1999
Highly Cited
1999
CCR5 and CXCR4 are the major HIV-1 coreceptors for R5 and X4 HIV-1 strains, respectively, and a threshold number of CD4 and… Expand
Highly Cited
1997
Highly Cited
1997
Bicyclams are a novel class of antiviral compounds which are highly potent and selective inhibitors of the replication of HIV-1… Expand
Highly Cited
1996
Highly Cited
1996
A cofactor for HIV-1 (human immunodeficiency virus-type 1) fusion and entry was identified with the use of a novel functional… Expand
Highly Cited
1996
Highly Cited
1996
Entry of human immunodeficiency virus type 1 (HIV-1) into cells requires binding to CD4 and fusion with a cellular membrane… Expand
Highly Cited
1996
Highly Cited
1996
A panel of primary syncytium-inducing (SI) human immunodeficiency virus type 1 isolates that infected several CD4+ T-cell lines… Expand
Highly Cited
1996
Highly Cited
1996
Accessory cell-surface molecules involved in the entry of human immunodeficiency virus-type 1 into cells have recently been… Expand
Highly Cited
1994
Highly Cited
1994
Several chemotactic agonists including interleukin-8 (IL-8) and related cytokines have been shown to activate and attract… Expand
Highly Cited
1993
Highly Cited
1993
A family of proinflammatory cytokines sharing several structural features has been described and includes, for example… Expand