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CXCR1 gene
Known as:
CDw128a
, C-X-C motif chemokine receptor 1
, IL8RA
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This gene is involved in pro-inflammatory cytokine cellular responses and neutrophil activation.
National Institutes of Health
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Related topics
Related topics
12 relations
C-X-C Chemokine Receptor Type 1, human
Chemotaxis
Cytokine Signaling Process
G Protein-Coupled Receptor Signaling
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Narrower (1)
IL8RA wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
CXCR1 and SLC11A1 polymorphisms affect susceptibility to cutaneous leishmaniasis in Brazil: a case-control and family-based study
L. Castellucci
,
L. Castellucci
,
+12 authors
Jenefer M. Blackwell
BMC Medical Genetics
2010
Corpus ID: 5953539
BackgroundL. braziliensis causes cutaneous (CL) and mucosal (ML) leishmaniasis. Wound healing neutrophil (PMN) and macrophage…
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2007
2007
Thermodynamic characterization of interleukin‐8 monomer binding to CXCR1 receptor N‐terminal domain
Harshica Fernando
,
G. Nagle
,
K. Rajarathnam
The FEBS Journal
2007
Corpus ID: 32708972
Chemokines elicit their function by binding receptors of the G‐protein‐coupled receptor class, and the N‐terminal domain (N…
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2007
2007
Secrets of a superbug
F. Lowy
Nature Network Boston
2007
Corpus ID: 26647226
Two studies examine why community-acquired strains of Staphylococcus aureus are so good at burrowing into flesh and wreaking…
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Highly Cited
2005
Highly Cited
2005
Cloning and characterization of mouse homolog of the CXC chemokine receptor CXCR1.
W. Fu
,
Yu Zhang
,
Jun Zhang
,
Weifeng Chen
Cytokine
2005
Corpus ID: 40925433
Highly Cited
2004
Highly Cited
2004
Expression of CXCR1 and CXCR2 receptors in malignant melanoma with different metastatic potential and their role in interleukin-8 (CXCL-8)-mediated modulation of metastatic phenotype
M. Varney
,
Aihua Li
,
B. Dave
,
C. Bucana
,
S. Johansson
,
Rakesh K. Singh
Clinical and Experimental Metastasis
2004
Corpus ID: 7991170
In the present study, we examined the autocrine/paracrine role of IL-8 in melanoma growth and metastasis by analyzing the…
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Highly Cited
2003
Highly Cited
2003
Interleukin-8-mediated Heterologous Receptor Internalization Provides Resistance to HIV-1 Infectivity
R. Richardson
,
K. Tokunaga
,
R. Marjoram
,
T. Sata
,
R. Snyderman
Journal of Biological Chemistry
2003
Corpus ID: 31792060
Human immunodeficiency virus type 1 (HIV-1) entry into CD4+ cells requires the chemokine receptors CCR5 or CXCR4 as co-fusion…
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2003
2003
Widely expressed transcripts for chemokine receptor CXCR1 in identified glutamatergic, γ‐aminobutyric acidergic, and cholinergic neurons and astrocytes of the rat brain: A single‐cell reverse…
M. Danik
,
C. Puma
,
Rémi Quirion
,
Sylvain Williams
Journal of Neuroscience Research
2003
Corpus ID: 45051687
Increasing evidence suggests that the chemokine interleukin (IL)‐8/CXCL8 plays important roles in CNS development, neuronal…
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2002
2002
Expression of the Interleukin-8 Receptors CXCR1 and CXCR2 on Cord-Blood-Derived Cultured Human Mast Cells
H. Inamura
,
M. Kurosawa
,
A. Okano
,
H. Kayaba
,
M. Majima
International Archives of Allergy and Immunology
2002
Corpus ID: 10993589
Background: An increase in mast cell number at sites of inflamed tissues has been observed. However, the expression of CXC…
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Highly Cited
2000
Highly Cited
2000
Regulation of the Human Chemokine Receptor CCR1
R. Richardson
,
Bryan C. Pridgen
,
B. Haribabu
,
R. Snyderman
Journal of Biological Chemistry
2000
Corpus ID: 21832857
To investigate the regulation of the CCR1 chemokine receptor, a rat basophilic leukemia (RBL-2H3) cell line was modified to…
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Highly Cited
1997
Highly Cited
1997
IL‐8 single‐chain homodimers and heterodimers: Interactions with the chemokine receptors CXCR1, CXCR2, and DARC
S. Leong
,
C. Hébert
,
+5 authors
R. McDowell
Protein Science
1997
Corpus ID: 41098379
Covalent single‐chain dimers of the chemokine interleukin‐8 (IL‐8) have been designed to mimic the dimeric form of IL‐8 in…
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