CXCR1 gene

Known as: CDw128a, C-X-C motif chemokine receptor 1, IL8RA 
This gene is involved in pro-inflammatory cytokine cellular responses and neutrophil activation.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
CXCR1 is one of two high-affinity receptors for the CXC chemokine interleukin-8 (IL-8), a major mediator of immune and… (More)
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Highly Cited
2010
Highly Cited
2010
Recent evidence suggests that breast cancer and other solid tumors possess a rare population of cells capable of extensive self… (More)
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Highly Cited
2009
Highly Cited
2009
The aggressiveness of malignant melanoma is associated with differential expression of CXCL-8 and its receptors, CXCR1 and CXCR2… (More)
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Highly Cited
2007
Highly Cited
2007
Interleukin-8 (IL-8) activates neutrophils via the chemokine receptors CXCR1 and CXCR2. However, the airways of individuals with… (More)
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Highly Cited
2007
Highly Cited
2007
Hypoxic cancer cells are resistant to treatment, leading to the selection of cells with a more malignant phenotype. The… (More)
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Highly Cited
2007
Highly Cited
2007
Sch527123 [2-hydroxy-N,N-dimethyl-3-[[2-[[1(R)-(5-methyl-2-furanyl)propyl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]ben-zamide] is… (More)
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Highly Cited
2006
Highly Cited
2006
We examined the expression of CXCL8 (interleukin-8), its receptors, CXCR1 and CXCR2, and vessel density in human melanoma by… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE We characterized interleukin-8 (IL-8) and IL-8 receptor expression (CXCR1 and CXCR2) in prostate cancer to address their… (More)
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Highly Cited
2004
Highly Cited
2004
The chemokine CXC ligand 8 (CXCL8)/IL-8 and related agonists recruit and activate polymorphonuclear cells by binding the CXC… (More)
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Highly Cited
2001
Highly Cited
2001
Stimulation of microvascular endothelial cells with interleukin (IL)-8 leads to cytoskeletal reorganization, which is mediated by… (More)
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