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CXCR1 gene

Known as: CDw128a, C-X-C motif chemokine receptor 1, IL8RA 
This gene is involved in pro-inflammatory cytokine cellular responses and neutrophil activation.
National Institutes of Health

Related topics

Related topics

12 relations
C-X-C Chemokine Receptor Type 1, humanChemotaxisCytokine Signaling ProcessG Protein-Coupled Receptor Signaling

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IL8RA wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Thermodynamic characterization of interleukin‐8 monomer binding to CXCR1 receptor N‐terminal domain
Chemokines elicit their function by binding receptors of the G‐protein‐coupled receptor class, and the N‐terminal domain (N… 
2007
2007
Secrets of a superbug
Two studies examine why community-acquired strains of Staphylococcus aureus are so good at burrowing into flesh and wreaking… 
2006
2006
N,N'-Diarylcyanoguanidines as antagonists of the CXCR2 and CXCR1 chemokine receptors.
Highly Cited
2005
Highly Cited
2005
Cloning and characterization of mouse homolog of the CXC chemokine receptor CXCR1.
Highly Cited
2004
Highly Cited
2004
Expression of CXCR1 and CXCR2 receptors in malignant melanoma with different metastatic potential and their role in interleukin-8 (CXCL-8)-mediated modulation of metastatic phenotype
In the present study, we examined the autocrine/paracrine role of IL-8 in melanoma growth and metastasis by analyzing the… 
2003
2003
Widely expressed transcripts for chemokine receptor CXCR1 in identified glutamatergic, γ‐aminobutyric acidergic, and cholinergic neurons and astrocytes of the rat brain: A single‐cell reverse…
Increasing evidence suggests that the chemokine interleukin (IL)‐8/CXCL8 plays important roles in CNS development, neuronal… 
2002
2002
Expression of the Interleukin-8 Receptors CXCR1 and CXCR2 on Cord-Blood-Derived Cultured Human Mast Cells
Background: An increase in mast cell number at sites of inflamed tissues has been observed. However, the expression of CXC… 
2002
2002
Intracellular trafficking of human CXCR1 and CXCR2: regulation by receptor domains and actin‐related kinases
In this study we investigated the regulation of CXCR1 and CXCR2 intracellular trafficking. First, we produced a chimeric CXCR2… 
1999
1999
CD45 modulation of CXCR1 and CXCR2 in human polymorphonuclear leukocytes
All leukocytes express the cell surface glycoprotein CD45, which has intrinsic intracellular protein tyrosine phosphatase… 
Highly Cited
1997
Highly Cited
1997
IL‐8 single‐chain homodimers and heterodimers: Interactions with the chemokine receptors CXCR1, CXCR2, and DARC
Covalent single‐chain dimers of the chemokine interleukin‐8 (IL‐8) have been designed to mimic the dimeric form of IL‐8 in… 
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