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CTGF wt Allele

Known as: IGFBP8, HCS24, CCN2 
Human CTGF wild-type allele is located in the vicinity of 6q23.1 and is approximately 3 kb in length. This allele, which encodes connective tissue… 
National Institutes of Health

Related topics

Related topics

8 relations
6q23.1Cell Differentiation processCell Proliferation Regulatory ProcessHomo sapiens

Broader (1)

CTGF gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Inhibition of connective tissue growth factor (CTGF/CCN2) in gallbladder cancer cells leads to decreased growth in vitro
Gallbladder cancer (GBC) is an aggressive neoplasm associated with late diagnosis, unsatisfactory treatment and poor prognosis… 
2012
2012
Hemizygous deletion of CTGF/CCN2 does not suffice to prevent fibrosis of the severely injured kidney.
2010
2010
Plasma CCN2/connective tissue growth factor is associated with right ventricular dysfunction in patients with neuroendocrine tumors
BackgroundCarcinoid heart disease, a known complication of neuroendocrine tumors, is characterized by right heart fibrotic… 
Highly Cited
2009
Highly Cited
2009
Adverse effects of high glucose and free fatty acid on cardiomyocytes are mediated by connective tissue growth factor.
Diabetic cardiomyopathy is characterized by interstitial fibrosis and cardiomyocyte hypertrophy and apoptosis. Also known as CCN2… 
Highly Cited
2009
Highly Cited
2009
Rac Inhibition Reverses the Phenotype of Fibrotic Fibroblasts
Background Fibrosis, the excessive deposition of scar tissue by fibroblasts, is one of the largest groups of diseases for which… 
Highly Cited
2008
Highly Cited
2008
Functional requirement of CCN2 for intramembranous bone formation in embryonic mice.
2008
2008
Promotion of Hydroxyapatite-Associated, Stem Cell-Based Bone Regeneration by CCN2
Multiple roles have been already recognized for CCN2 in cartilage development and regeneration. However, the effects of CCN2 on… 
2008
2008
Focal Adhesion Kinase/Src Suppresses Early Chondrogenesis
Adhesive signaling plays a key role in cellular differentiation, including in chondrogenesis. Herein, we probe the contribution… 
2007
2007
Role of CCN2/CTGF in the proliferation of Mastomys enterochromaffin-like cells and gastric carcinoid development.
Mastomys enterochromaffin-like (ECL) cell proliferation is initially gastrin driven, but once neoplasia develops, cells become… 
2006
2006
Multiple activation of mitogen-activated protein kinases by purified independent CCN2 modules in vascular endothelial cells and chondrocytes in culture.
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