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A nuclear DNA phylogenetic perspective on the evolution of echolocation and historical biogeography of extant bats (chiroptera).
TLDR
195 morphological characters were evaluated and a morphological synapomorphy characterizing the Rhinolophoidea was identified and is suggestive of a separate origin of echolocation in this clade, as well as the center of origin of modern-day bat families.
Protein Evolution by Molecular Tinkering: Diversification of the Nuclear Receptor Superfamily from a Ligand-Dependent Ancestor
Phylogenetic reconstruction of the structure and function of the ancestor of the nuclear receptor protein family reveals how functional diversity evolves by subtle tinkering with an ancestral
The molecular genetics of gastroenteropancreatic neuroendocrine tumors
TLDR
Divergence in gene expression patterns in the development of GI carcinoids and PETs was identified, whereas examination of the PET and GI carcinoid data demonstrated only few areas of overlap in the accumulation of genetic aberrations, which suggest that the recent World Health Organization classification of GEP‐NETs may require updating.
Evolution of Minimal Specificity and Promiscuity in Steroid Hormone Receptors
Most proteins are regulated by physical interactions with other molecules; some are highly specific, but others interact with many partners. Despite much speculation, we know little about how and why
GENETIC AND PHENOTYPIC DIFFERENCES BETWEEN SOUTH AFRICAN LONG-FINGERED BATS, WITH A GLOBAL MINIOPTERINE PHYLOGENY
TLDR
Examination of the global taxonomy of Miniopterus confirms that Schreibers's long-fingered bat forms a paraphyletic species complex and supports the elevation of M. natalensis to full species rank.
The functional characterization of normal and neoplastic human enterochromaffin cells.
TLDR
These data support novel methodology to purify live human EC cells for functional characterization and transcriptome assessment, which will allow identification of new targets to control the secretion and proliferation of SI carcinoids.
Therapeutic options for gastrointestinal carcinoids.
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