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CS 518

Known as: CS-518 
National Institutes of Health

Related topics

Related topics

1 relation
RS 5186

Papers overview

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2004
2004
Changes in plasma and urinary 11-dehydrothromboxane B2 in healthy subjects produced by oral CS-518, a novel thromboxane synthase inhibitor
SummaryWhen 50 mg CS-518, a novel thromboxane (TX) A2 synthase inhibitor, was orally administered to healthy male volunteers, the… 
2001
2001
Effect of thromboxane A2 (TXA2) synthase inhibitor and TXA2 receptor antagonist alone and in combination on antigen-induced bronchoconstriction in guinea pigs.
2000
2000
Effect of thromboxane synthase inhibitor, CS-518, on propranolol-induced bronchoconstriction in guinea pigs.
Beta-adrenoreceptor antagonists, such as propranolol, can provoke severe bronchoconstriction in asthmatic subjects. Recently we… 
1993
1993
Effects of CS-518, a thromboxane synthase inhibitor, on eosinophil function.
1993
1993
Effects of CS-518, a thromboxane synthase inhibitor, on the asthmatic response.
1993
1993
Alteration of eicosanoid production in the sensitized guinea pig lung by CS-518.
1993
1993
Superiority of plasma 11-dehydro-TXB2 to TXB2 as an index of in vivo TX formation in rabbits after dosing of CS-518, a TX synthase inhibitor.
1993
1993
Change in responsiveness of airway and beta-adrenoceptor in guinea pigs.
Allergen inhalation challenge resulted in significant (p < 0.05) increase in airway responsiveness to methacholine soon after… 
1992
1992
Enzyme-linked immunosorbent assay of CS-518, a thromboxane synthetase inhibitor, in rabbit plasma and platelets.
A competitive enzyme-linked immunosorbent assay (ELISA) was developed for determination of CS-518, a novel thromboxane synthetase… 
1991
1991
In vitro antiplatelet profiles of the new thromboxane synthetase inhibitor sodium 2-(1-imidazolylmethyl)-4,5-dihydrobenzo[b]thiophene-6-carboxylate.
The in vitro properties of CS-518 (RS-5186; sodium 2-(1-imidazolylmethyl)- 4,5-dihydrobenzo[b]thiophene-6-carboxylate, CAS 113817… 
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