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RS 5186

Known as: Benzo(b)thiophene-6-carboxylic acid, 4,5-dihydro-2-(1H-imidazol-1-ylmethyl)-, sodium salt, RS-5186 
National Institutes of Health

Related topics

Related topics

5 relations
CS 518

Broader (4)

Enzyme InhibitorsNeuroprotective AgentsPlatelet Aggregation InhibitorsThiophenes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1999
1999
Effects of thromboxane synthetase inhibitor (RS-5186) on experimentally-induced cerebral vasospasm.
RS-5186, which inhibits thromboxane A2 (TXA2) synthetase activity, ameliorated delayed cerebral vasospasm in a canine two… 
1994
1994
Prostaglandin H2 as an endothelium‐derived contracting factor modulates endothelin‐1-induced contraction
Objective To investigate the possible involvement of prostaglandin H2, an endothelium-derived contracting factor in the rat aorta… 
1993
1993
Somatostatin-induced contraction mediated by endothelial TXA2 production in canine cerebral arteries.
1989
1989
Pharmacological manipulation of inflammation in rabbit hydronephrosis: effects of a combined cyclooxygenase/lipoxygenase inhibitor ethoxyquin, a thromboxane synthase inhibitor RS-5186 and a PAF…
The rabbit hydronephrotic kidney (HNK) is a model of renal inflammation characterized by a marked increase in arachidonic acid… 
1989
1989
RS-5186, a novel, long-acting thromboxane synthetase inhibitor.
1989
1989
Vasorelaxing effects of prostaglandin I2 on the canine basilar and coronary arteries.
The effects of prostaglandin (PG) I2 on canine basilar and coronary arteries were studied. PGI2 caused a relaxation from the… 
1988
1988
Myocardial salvage by a novel thromboxane A2 synthetase inhibitor in a canine coronary occlusion-reperfusion model.
The effects of the new thromboxane A2 (TXA2) synthetase inhibitor sodium 6-(2-[1-(1H)-imidazolyl]methyl-4,5-dihydrobenzo[b… 
1988
1988
RS-5186, a novel thromboxane synthetase inhibitor with a potent and extended duration of action.
1988
1988
Effect of a novel thromboxane A2 synthetase inhibitor on ischemia-induced mitochondrial dysfunction in canine hearts.
This study was designed to determine the effect of sodium 6-(2-[1-(1H)-imidazolyl]methyl-4,5-dihydrobenzo[b] thiophene… 
1988
1988
In Vitro Activity of Novel 5‐Carbonyl Derivatives of 3‐Phenyl‐3‐(1H‐imidazol‐1‐ylmethyl)‐2‐methyl‐isoxazolidines a
As part of our continuing search for novel antifungal agents, a number of 3,ssubstituted isoxazolidine compounds were prepared… 
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