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CRADD gene

Known as: RAIDD, RIP-associated ICH1/CED3-homologous protein with death domain, CRADD 
National Institutes of Health

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1 relation
CRADD protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Regulation of CRADD-caspase 2 cascade by histone deacetylase 1 in gastric cancer.
CRADD, also referred as RAIDD, is an adaptor protein that could interact with both caspase 2 and RIP that can promote apoptosis… 
2013
2013
PIDD mediates and stabilizes the interaction between RAIDD and Caspase-2 for the PIDDosome assembly
The PIDDosome, which is an oligomeric signaling complex composed of PIDD, RAIDD and caspase-2, can induce proximity-based… 
2009
2009
Purification, Crystallization and Preliminary X-ray Crystallographic Studies of RAIDD Death-Domain (DD)
Caspase-2 activation by formation of PIDDosome is critical for genotoxic stress induced apoptosis. PIDDosome is composed of three… 
2007
2007
Crystallization and preliminary X-ray crystallographic studies of the oligomeric death-domain complex between PIDD and RAIDD.
Three large macromolecular complexes known as the death-inducing signaling complex (DISC), the apoptosome and the PIDDosome… 
2006
2006
TSA-induced cell death in prostate cancer cell lines is caspase-2 dependent and involves the PIDDosome
The histone deacetylase inhibitor Trichostatin A (TSA) has previously been found to induce caspase activity in the human prostate… 
2006
2006
RAIDD is required for apoptosis of PC12 cells and sympathetic neurons induced by trophic factor withdrawal
Caspase 2 has been implicated in trophic deprivation-induced neuronal death. We have shown that overexpression of the caspase 2… 
2003
2003
Overexpression of Raidd cDNA inhibits differentiation of mouse preadipocytes
Abstract. RAIDD (RIP‐associated ICH‐1 homologous protein with a death domain) is an adaptor molecule that mediates the action of… 
2000
2000
Identification of a caspase-2 isoform that behaves as an endogenous inhibitor of the caspase cascade.
Procaspase-2 is one of the aspartate-specific cysteine proteases that are activated in response to various apoptotic stimuli. Two… 
1998
1998
A 500-kb YAC and BAC contig encompassing the high-growth deletion in mouse chromosome 10 and identification of the murine Raidd/Cradd gene in the candidate region.
The mouse high growth (hg) gene was identified in a selection experiment for rapid growth. It produces a 30-50% increase in… 
1998
1998
Adenoviral inhibitors of the apoptotic cascade.
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