Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

CR002

 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Monoclonal Antibodies

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Safety and efficacy of a novel Prunus domestica extract (Sitoprin, CR002) on testosterone-induced benign prostatic hyperplasia (BPH) in male Wistar rats
Abstract The efficacy of a novel Prunus domestica bark extract (Sitoprin, CR002) was investigated on testosterone propionate (TP… Expand
2015
2015
Efficacy of Novel Pygeum Extract (CR002) on Testosterone-Induced Benign Prostatic Hyperplasia (BPH) in Male Wistar Rats
 
Review
2010
Review
2010
Emerging roles of PDGF-D signaling pathway in tumor development and progression.
Platelet-derived growth factor-D (PDGF-D) can regulate many cellular processes, including cell proliferation, apoptosis… Expand
  • figure 1
  • figure 2
2008
2008
A phase I study of CR002, a fully-human monoclonal antibody against platelet-derived growth factor-D.
OBJECTIVE To investigate the safety, pharmacokinetics (PK), binding activity and immunogenicity of CR002, a human monoclonal… Expand
Highly Cited
2007
Highly Cited
2007
PDGF-D inhibition by CR002 ameliorates tubulointerstitial fibrosis following experimental glomerulonephritis.
BACKGROUND Arresting or regressing kidney scarring is of major clinical relevance. Platelet-derived growth factor D (PDGF-D) is… Expand
  • table 1
  • figure 1
  • figure 2
  • table 2
  • figure 3
Highly Cited
2006
Highly Cited
2006
Antagonism of PDGF-D by human antibody CR002 prevents renal scarring in experimental glomerulonephritis.
Glomerular mesangial cell proliferation and/or matrix accumulation characterizes many progressive renal diseases. PDGF-D was… Expand
  • table 1
  • table 2
  • figure 1
  • table 3
  • table 4
Highly Cited
2003
Highly Cited
2003
A fully human monoclonal antibody (CR002) identifies PDGF-D as a novel mediator of mesangioproliferative glomerulonephritis.
PDGF-B is of central importance in mesangioproliferative diseases. PDGF-D, a new PDGF isoform, like PDGF-B, signals through the… Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE