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CR 1409

Known as: CR-1409 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

lorglumide

Papers overview

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Highly Cited
2001
Highly Cited
2001
Intestinal serotonin acts as paracrine substance to mediate pancreatic secretion stimulated by luminal factors.
We recently demonstrated that luminal factors such as osmolality, disaccharides, and mechanical stimulation evoke pancreatic… 
1991
1991
Effects of bombesin on the development of N-nitrosobis(2-oxopropyl)amine-induced pancreatic lesions in hamsters.
1991
1991
The Effect of the CCK Receptor Antagonist CR 1409 on Bile Reflux Pancreatitis in the Opossum
Availability of specific cholecystokinin (CCK) receptor antagonists has the potential for contributing to delineation of the role… 
Highly Cited
1990
Highly Cited
1990
Role of cholecystokinin in the development of BOP-induced pancreatic lesions in hamsters.
Cholecystokinin (CCK) has been shown to promote pancreatic growth and azaserine-induced pancreatic carcinogenesis in rats. The… 
Highly Cited
1989
Highly Cited
1989
Influence of cholecystokinin antagonist on the effects of cholecystokinin and bombesin on azaserine-induced lesions in rat pancreas.
1989
1989
Modulation by CR-1409 (lorglumide), a cholecystokinin receptor antagonist, of trypsin inhibitor-enhanced growth of azaserine-induced putative preneoplastic lesions in rat pancreas.
Feeding of raw soya flour or other trypsin inhibitors such as camostate is a well-established method for promoting growth of (pre… 
1989
1989
Pharmacological and mechanistic studies of cholecystokinin-facilitated [3H]dopamine efflux from rat nucleus accumbens
1989
1989
Study into the role of cholecystokinin in bombesin-stimulated pancreatic growth in rats and hamsters.
Highly Cited
1989
Highly Cited
1989
Interactions between Bile and Pancreatic Juice Diversions on Cholecystokinin Release and Pancreas in Conscious Rats
Abstract Pancreatic exocrine secretion in the conscious rat is regulated by proteases secreted by the pancreas, and… 
1987
1987
CR‐1409: A Potent Inhibitor of Cholecystokinin‐Stimulated Amylase Release and Cholecystokinin Binding in Rat Pancreatic Acini
The effects of a new glutaramic acid derivative, 3,4-dichloro-benzamido-N, N-dipentyl-glutaramic acid (CR-1409), on… 
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