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CP 100,263

Known as: CP 100263, CP-100,263, CP-100263 
National Institutes of Health

Papers overview

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2000
2000
The site of the anti-emetic action of the neurokinin1 receptor antagonist CP-99,994 was studied in the ferret using the centrally… Expand
Highly Cited
1999
Highly Cited
1999
The intraplantar injection of lysophosphatidic acid (LPA) at doses of 0.1-100 pmol into the hind limb of mice showed dose… Expand
1999
1999
The intraplantar injection of kyotorphin (Kyo) elicited nociceptive flexor responses in mice in a dose-dependent manner between 0… Expand
Highly Cited
1999
Highly Cited
1999
The anti-emetic potential of CP-122,721 ((+)-2S,3S)-3-(2-methoxy-5-trifluoromethoxybenzyl)amino-2-phenylpi peridine), CP-99,994… Expand
Highly Cited
1995
Highly Cited
1995
1 The selective NK1 receptor antagonist, CP‐99,994, produced dose‐related (0.1‐1.0 mg kg−1, s.c.) inhibition of vomiting and… Expand
1995
1995
1 The ability of CP‐99,994, and its less active enantiomer, CP‐100,263, to inhibit spontaneous behaviours and hyperalgesia… Expand
Highly Cited
1994
Highly Cited
1994
These studies have examined the effects of the selective neurokinin1 (NK1) receptor antagonist CP-99,994 on the retching and… Expand
1994
1994
We have examined the antinociceptive activity of the potent and selective tachykinin NK1 receptor antagonist, CP-99,994, and its… Expand
Highly Cited
1994
Highly Cited
1994
The in vivo pharmacological profiles of the selective tachykinin NK1 receptor agonists, [Sar9,Met(O2)11]substance P and GR 73632… Expand
1994
1994
Evidence that tachykinin NK1 receptors selectively modulate activity in the mesolimbic dopamine pathway suggests an antipsychotic… Expand