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COX14 gene

Known as: COX14, CHROMOSOME 12 OPEN READING FRAME 62, COX14 cytochrome c oxidase assembly factor 
National Institutes of Health

Papers overview

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2017
2017
A CMC1‐knockout reveals translation‐independent control of human mitochondrial complex IV biogenesis
Defects in mitochondrial respiratory chain complex IV (CIV) frequently cause encephalocardiomyopathies. Human CIV assembly… 
2013
2013
Mss 51 p and Cox 14 p jointly regulate mitochondrial Cox 1 p expression in Saccharomyces cerevisiae
Mutations in SURF1, the human homologue of yeast SHY1, are responsible for Leigh’s syndrome, a neuropathy associated with… 
Highly Cited
2012
Highly Cited
2012
Mutations in C12orf62, a factor that couples COX I synthesis with cytochrome c oxidase assembly, cause fatal neonatal lactic acidosis.
Highly Cited
2010
Highly Cited
2010
Cox25 Teams Up with Mss51, Ssc1, and Cox14 to Regulate Mitochondrial Cytochrome c Oxidase Subunit 1 Expression and Assembly in Saccharomyces cerevisiae*
In the yeast Saccharomyces cerevisiae, mitochondrial cytochrome c oxidase (COX) biogenesis is translationally regulated. Mss51, a… 
Highly Cited
2010
Highly Cited
2010
Coa3 and Cox14 are essential for negative feedback regulation of COX1 translation in mitochondria
Coa3 and Cox14 form assembly intermediates with newly synthesized Cox1 and are required for association of the Mss51… 
Review
2010
Review
2010
The Carboxyl-terminal End of Cox1 Is Required for Feedback Assembly Regulation of Cox1 Synthesis in Saccharomyces cerevisiae Mitochondria*
Synthesis of the largest cytochrome c oxidase (CcO) subunit, Cox1, on yeast mitochondrial ribosomes is coupled to assembly of CcO… 
Highly Cited
2009
Highly Cited
2009
Dual functions of Mss51 couple synthesis of Cox1 to assembly of cytochrome c oxidase in Saccharomyces cerevisiae mitochondria.
Functional interactions of the translational activator Mss51 with both the mitochondrially encoded COX1 mRNA 5'-untranslated… 
Highly Cited
2007
Highly Cited
2007
Shy1 couples Cox1 translational regulation to cytochrome c oxidase assembly
Cytochrome c oxidase (complex IV) of the respiratory chain is assembled from nuclear and mitochondrially‐encoded subunits… 
Highly Cited
2004
Highly Cited
2004
Mss51p and Cox14p jointly regulate mitochondrial Cox1p expression in Saccharomyces cerevisiae
Mutations in SURF1, the human homologue of yeast SHY1, are responsible for Leigh's syndrome, a neuropathy associated with… 
Highly Cited
1995
Highly Cited
1995
Cloning and Characterization of COX14, Whose Product Is Required for Assembly of Yeast Cytochrome Oxidase (*)
Nuclear respiration-deficient mutants of Saccharomyces cerevisiae previously assigned to complementation group G93 lack… 
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