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COPS6 gene

Known as: MOV34-34KD, COP9 subunit 6 (MOV34 homolog, 34 kD), COP9 Signalosome Subunit 6 Gene 
This gene is involved in signalosome function.
National Institutes of Health

Related topics

Related topics

4 relations
COPS6 protein, humanCOPS7A geneDeubiquitinationSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
COP9 signalosome subunit 6 mediates PDGF ‐induced pulmonary arterial smooth muscle cells proliferation
2018
2018
COP9 signalosome subunit 5 regulates cancer metastasis by deubiquitinating SNAIL
Cancer metastasis is a major cause of mortality in cancer patients. The transcription factor SNAIL plays an important role in… 
2017
2017
Genome-wide analysis of gene expression profiling revealed that COP9 signalosome is essential for correct expression of Fe homeostasis genes in Arabidopsis
In plant cells, either excess or insufficient iron (Fe) concentration triggers stress responses, therefore it is strictly… 
2015
2015
CSN6 positively regulates c-Jun in a MEKK1-dependent manner
c-Jun is a proto-oncoprotein that is commonly overexpressed in many types of cancer and is believed to regulate cell… 
2012
2012
A novel link between the HER2-Akt and MDM2-p53 pathways via CSN6
The constitutive photomorphogenesis 9 (COP9) signalosome (CSN) is an evolutionarily conserved multiprotein complex in plants and… 
2008
2008
The COP9 signalosome-mediated deneddylation is stimulated by caspases during apoptosis
In concert with the ubiquitin (Ub) proteasome system (UPS) the COP9 signalosome (CSN) controls the stability of cellular… 
2007
2007
Arabidopsis eIF3e is regulated by the COP9 signalosome and has an impact on development and protein translation.
The roles of individual eukaryotic translation initiation factor 3 (eIF3) subunits are largely unclear, although some are… 
2005
2005
Growth suppression induced by the TRC8 hereditary kidney cancer gene is dependent upon JAB1/CSN5
TRC8 encodes an E3-ubiquitin ligase disrupted in a family with hereditary renal cell carcinoma (RCC). We previously reported that… 
2002
2002
Polyamine-modulated factor 1 binds to the human homologue of the 7a subunit of the Arabidopsis COP9 signalosome: implications in gene expression.
Polyamines have been identified to play a role in the transcription of various growth-related genes. The recently discovered… 
2000
2000
A gain-of-function phenotype conferred by over-expression of functional subunits of the COP9 signalosome in Arabidopsis.
The COP9 signalosome is a conserved cellular regulator present in diverse organisms. To understand the structural and functional… 
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