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CLK4 gene

Known as: CDC like kinase 4, CDC-LIKE KINASE 4, CLK4 
National Institutes of Health

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CDC-like kinase 4

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Exploration of the imidazo[1,2-b]pyridazine scaffold as a protein kinase inhibitor.
2013
2013
Small-molecule pyrimidine inhibitors of the cdc2-like (Clk) and dual specificity tyrosine phosphorylation-regulated (Dyrk) kinases: development of chemical probe ML315.
2012
2012
Library-based Discovery of DYRK1A/CLK1 Inhibitors from Natural Product Extracts
Abstract The dual specificity tyrosine-phosphorylation-regulated kinase DYRK1A possesses diverse roles in neuronal development… 
Highly Cited
2011
Highly Cited
2011
Potent and selective small molecule inhibitors of specific isoforms of Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk).
Highly Cited
2009
Highly Cited
2009
Evaluation of substituted 6-arylquinazolin-4-amines as potent and selective inhibitors of cdc2-like kinases (Clk).
2009
2009
Comparison of bioluminescent kinase assays using substrate depletion and product formation.
Assays for ATPases have been enabled for high-throughput screening (HTS) by employing firefly luciferase to detect the remaining… 
2008
2008
TTK/Mps1 controls nuclear targeting of c-Abl by 14-3-3-coupled phosphorylation in response to oxidative stress
Upon exposure to genotoxic stress, the c-Abl tyrosine kinase is released from cytoplasmic 14-3-3 proteins and then is targeted to… 
2003
2003
Structural analysis of UBL5, a novel ubiquitin‐like modifier
UBL5 is a widely expressed human protein that is strongly conserved across phylogeny. Orthologs of UBL5 occur in every eukaryotic… 
2003
2003
Beacon interacts with cdc2/cdc28-like kinases.
2002
2002
Novel SR-rich-related Protein Clasp Specifically Interacts with Inactivated Clk4 and Induces the Exon EB Inclusion of Clk*
We identified a novel serine/arginine (SR)-rich-related protein as a binding partner of Clk4 mutant lacking kinase activity (Clk4… 
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