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  • Andrew S. Rosenthal, C. Tanega, +7 authors Craig J Thomas
  • Chemistry, Medicine
  • Bioorganic & medicinal chemistry letters
  • 2011 (First Publication: 1 May 2011)
  • Continued examination of substituted 6-arylquinazolin-4-amines as Clk4 inhibitors resulted in selective inhibitors of Clk1, Clk4, Dyrk1A and Dyrk1B. Several of the most potent inhibitors wereContinue Reading
  • Andrew S. Rosenthal, Thomas S. Dexheimer, +6 authors David J. Maloney
  • Chemistry, Medicine
  • Bioorganic & medicinal chemistry letters
  • 2013 (First Publication: 1 October 2013)
  • Human cells utilize a variety of complex DNA repair mechanisms in order to combat constant mutagenic and cytotoxic threats from both exogenous and endogenous sources. The RecQ family of DNAContinue Reading
  • Carmony L. Hartwig, Andrew S. Rosenthal, John J. D'Angelo, Carol E Griffin, Gary H. Posner, Roland Arthur Cooper
  • Chemistry, Medicine
  • Biochemical pharmacology
  • 2009 (First Publication: 1 February 2009)
  • The antimalarial trioxanes, exemplified by the naturally occurring sesquiterpene lactone artemisinin and its semi-synthetic derivatives, contain an endoperoxide pharmacophore that lends tremendousContinue Reading