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CKS1B gene

Known as: CDC28 PROTEIN KINASE 1B, CKS1, CDC28 protein kinase regulatory subunit 1B 
This gene plays a role in the regulation of cyclin dependent kinase activity.
National Institutes of Health

Related topics

Related topics

4 relations
Cell Cycle ControlCell Proliferation Regulatory ProcessCyclin-Dependent Kinases Regulatory Subunit 1G1/S Transition Checkpoint

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Loss of miR-1258 contributes to carcinogenesis and progression of liver cancer through targeting CDC28 protein kinase regulatory subunit 1B
Hepatocellular carcinoma (HCC) is the leading cause of cancer related death worldwide. The number of deaths is proportional to… 
2010
2010
CKS1B amplification is a frequent event in cutaneous squamous cell carcinoma with aggressive clinical behaviour
Genetic mechanisms giving rise to the development of cutaneous squamous cell carcinoma (cSCC) are poorly understood and… 
2006
2006
Folding and Fibril Formation of the Cell Cycle Protein Cks1*
The Saccharomyces cerevisiae Cks protein Cks1 has a COOH-terminal glutamine-rich sequence not present in other homologues. Cks… 
Highly Cited
2005
Highly Cited
2005
Amplification and overexpression of CKS1B at chromosome band 1q21 is associated with reduced levels of p27 Kip1 and an aggressive clinical course in multiple myeloma
Abstract The molecular basis for aggressive transformation of multiple myeloma (MM) and other cancers is not completely… 
2004
2004
Molecular and Biochemical Characterization of the Skp2-Cks1 Binding Interface*
SCFSkp2 is a multisubunit E3 ubiquitin ligase responsible for ubiquitination of cell cycle inhibitor p27. Ubiquitination of p27… 
2003
2003
A Negatively Charged Amino Acid in Skp2 Is Required for Skp2-Cks1 Interaction and Ubiquitination of p27Kip1*
Proteolysis of cyclin-dependent kinase inhibitor p27 occurs predominately in the late G1 phase of the cell cycle through a… 
2003
2003
Weak cooperativity in the core causes a switch in folding mechanism between two proteins of the cks family.
2002
2002
Folding and association of the human cell cycle regulatory proteins ckshs1 and ckshs2.
The two human proteins ckshs1 and ckshs2 are each 79 amino acids in length and consist of a four-stranded beta-sheet capped at… 
2001
2001
Association of the cell cycle regulatory proteins p45(SKP2) and CksHs1. Functional effect on CDK2 complex formation and kinase activity.
In mammalian cells, CDK2 is part of a multiprotein complex that includes Cyclin A or E and cell cycle regulatory proteins such as… 
Highly Cited
1989
Highly Cited
1989
The Saccharomyces cerevisiae CKS1 gene, a homolog of the Schizosaccharomyces pombe suc1+ gene, encodes a subunit of the Cdc28 protein kinase complex
The Saccharomyces cerevisiae gene CDC28 encodes a protein kinase required for cell cycle initiation. In an attempt to identify… 
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