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CI 986
Known as:
CI-986
, Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with 5-(3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)-1,3,4-thiadiazole-2(3H)-thione (1:1)
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Thiadiazoles
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2000
2000
Role of Leukotrienes on Coronary Vasoconstriction in Isolated Hearts of Arthritic Rats: Effect of in vivo Treatment with CI-986, a Dual Inhibitor of Cyclooxygenase and Lipoxygenase
Ş. Gök
,
S. Ülker
,
A. Hüseyinov
,
F. B. Hatip
,
M. Çinar
,
A. Evinç
Pharmacology
2000
Corpus ID: 45312655
In this study, coronary perfusion pressure and force of contraction were investigated in isolated hearts removed from arthritic…
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1995
1995
Stimulus-dependent effects of CI-986 on arachidonic acid metabolism by human neutrophils
C. Wright
,
J. A. Kennedy
,
P. Kuipers
,
M. Ferin
Inflammation Research
1995
Corpus ID: 28088382
CI-986 (5-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-1,3,4-thiadiazole-2(3H)-thione, choline salt) was evaluated for its effect…
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1994
1994
The pharmacologic effects of 5-[3,5-bis(1,1-dimethylethyl)-4- hydroxyphenyl]-1,3,4-thiadiazole-2(3H)-thione, choline salt (CI-986), a novel inhibitor of arachidonic acid metabolism in models of…
D. Schrier
,
V. Baragi
,
+7 authors
M. C. Conroy
Prostaglandins
1994
Corpus ID: 20620743
Highly Cited
1993
Highly Cited
1993
Design of 5-(3,5-di-tert-butyl-4-hydroxyphenyl)-1,3,4-thiadiazoles, -1,3,4-oxadiazoles, and -1,2,4-triazoles as orally-active, nonulcerogenic antiinflammatory agents.
M. D. Mullican
,
M. Wilson
,
D. T. Connor
,
C. Kostlan
,
D. Schrier
,
R. Dyer
Journal of Medicinal Chemistry
1993
Corpus ID: 33392558
To discover dual inhibitors of 5-lipoxygenase (LO) and cyclooxygenase (CO) with improved pharmacokinetic properties, we have…
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1993
1993
Subacute and subchronic toxicology studies of CI-986, a novel anti-inflammatory compound.
D. Robertson
,
G. Loewen
,
+4 authors
E. Urda
Fundamental and Applied Toxicology
1993
Corpus ID: 24323828
CI-986 (5-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-1,3,4-thiadiazole-2(3H)- thione-2-hydroxy-N,N,N-trimethylethanaminium salt…
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