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CI 976

Known as: CI-976 
National Institutes of Health

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PD 128042

Papers overview

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2008
2008
The Lysophospholipid Acyltransferase Antagonist CI‐976 Inhibits a Late Step in COPII Vesicle Budding
The mechanism of coat protein (COP)II vesicle fission from the endoplasmic reticulum (ER) remains unclear. Lysophospholipid… 
2005
2005
A unique lysophospholipid acyltransferase (LPAT) antagonist, CI-976, affects secretory and endocytic membrane trafficking pathways
Previous studies have shown that inhibition of a Golgi-complex-associated lysophospholipid acyltransferase (LPAT) activity by the… 
2005
2005
Use of acyltransferase inhibitors to block vesicular traffic between the ER and Golgi complex.
2004
2004
Molecular cloning and biochemical characterization of Candida albicans acyl-CoA:sterol acyltransferase, a potential target of antifungal agents.
2004
2004
Characterization of a novel CI-976-sensitive lysophospholipid acyltransferase that is associated with the Golgi complex.
2001
2001
Influence of membrane partitioning on inhibitors of membrane-bound enzymes.
Membrane-water partitioning of inhibitors of acyl-coenzyme A:cholesterol acyltransferase (ACAT) governs the concentration of… 
1998
1998
Lipid-lowering effects of WAY-121,898, an inhibitor of pancreatic cholesteryl ester hydrolase
WAY-121,898 is an inhibitor of pancreatic cholesteryl ester hydrolase (pCEH). After confirming its in vitro potency and relative… 
1994
1994
Effect of the acyl-CoA:cholesterol acyltransferase inhibitor, E5324, on experimental atherosclerosis in rabbits.
1993
1993
Inhibition of acyl-CoA cholesterol O-acyltransferase reduces the cholesteryl ester enrichment of atherosclerotic lesions in the Yucatan micropig.
Highly Cited
1991
Highly Cited
1991
Comparison of CI-976, an ACAT inhibitor, and selected lipid-lowering agents for antiatherosclerotic activity in iliac-femoral and thoracic aortic lesions. A biochemical, morphological, and…
Due to the potential importance of acyl-coenzyme A:cholesterol O-acyltransferase (ACAT) in the generation of lipid-filled… 
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