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CHUK wt Allele

Known as: NFKBIKA, IKK1, Conserved Helix-Loop-Helix Ubiquitous Kinase wt Allele 
Human CHUK wild-type allele is located within 10q24-q25 and is approximately 80 kb in length. This allele, which encodes inhibitor of nuclear factor… Expand
National Institutes of Health

Papers overview

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Review
2006
Review
2006
The diverse cellular and biological functions of the nuclear factor kappa B (NF-κB) pathway, together with the catastrophic… Expand
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Review
2006
Review
2006
Transcription factors of the NF-κB family regulate hundreds of genes in the context of multiple important physiological and… Expand
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Highly Cited
2006
Highly Cited
2006
Activation of transcription factor NF-κB in the central nervous system (CNS) has been linked to autoimmune demyelinating disease… Expand
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Highly Cited
2003
Highly Cited
2003
The transcription factor NF-kappaB is implicated in various aspects of T cell development and function. The IkappaB kinase (IKK… Expand
Highly Cited
2002
Highly Cited
2002
Tumor necrosis factor (TNF)‐related apoptosis‐inducing ligand (TRAIL) induces apoptosis in a wide range of malignant cells… Expand
Highly Cited
2000
Highly Cited
2000
We investigated the inhibition of IkappaB kinase (IKK) activity in lipopolysaccharide (LPS)-activated murine macrophages (RAW 264… Expand
Highly Cited
2000
Highly Cited
2000
NF-kappaB activity is induced by cytokines, stress, and pathogens. IKK1 and IKK2 are critical IkappaB kinases in NF-kappaB… Expand
Highly Cited
1999
Highly Cited
1999
Phosphorylation of inhibitor of kappa B (IκB) proteins is an important step in the activation of the transcription nuclear factor… Expand
Highly Cited
1999
Highly Cited
1999
IkappaB kinases (IKKs) IKK1 and IKK2 are two putative IkappaBalpha kinases involved in NF-kappaB activation. To examine the in… Expand
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Highly Cited
1999
Highly Cited
1999
Phosphorylation of inhibitor of kappa B (IkappaB) proteins is an important step in the activation of the transcription nuclear… Expand