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CHUK wt Allele

Known as: NFKBIKA, IKK1, Conserved Helix-Loop-Helix Ubiquitous Kinase wt Allele 
Human CHUK wild-type allele is located within 10q24-q25 and is approximately 80 kb in length. This allele, which encodes inhibitor of nuclear factor… Expand
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Activation of transcription factor NF-κB in the central nervous system (CNS) has been linked to autoimmune demyelinating disease… Expand
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Highly Cited
2003
Highly Cited
2003
The transcription factor NF-kappaB is implicated in various aspects of T cell development and function. The IkappaB kinase (IKK… Expand
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Highly Cited
2003
Highly Cited
2003
ABSTRACT Antiapoptotic activity of NF-κB in tumors contributes to acquisition of resistance to chemotherapy. Degradation of IκB… Expand
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Highly Cited
2002
Highly Cited
2002
Tumor necrosis factor (TNF)‐related apoptosis‐inducing ligand (TRAIL) induces apoptosis in a wide range of malignant cells… Expand
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Review
2002
Review
2002
  • J. Lin
  • Archives of pharmacal research
  • 2002
  • Corpus ID: 20575541
The action mechanisms of several chemopreventive agents derived from herbal medicine and edible plants have become attractive… Expand
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Highly Cited
2000
Highly Cited
2000
We investigated the inhibition of IkappaB kinase (IKK) activity in lipopolysaccharide (LPS)-activated murine macrophages (RAW 264… Expand
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Highly Cited
2000
Highly Cited
2000
NF-kappaB activity is induced by cytokines, stress, and pathogens. IKK1 and IKK2 are critical IkappaB kinases in NF-kappaB… Expand
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Highly Cited
1999
Highly Cited
1999
Phosphorylation of inhibitor of kappa B (IκB) proteins is an important step in the activation of the transcription nuclear factor… Expand
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Highly Cited
1999
Highly Cited
1999
IkappaB kinases (IKKs) IKK1 and IKK2 are two putative IkappaBalpha kinases involved in NF-kappaB activation. To examine the in… Expand
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Highly Cited
1999
Highly Cited
1999
Phosphorylation of inhibitor of kappa B (IkappaB) proteins is an important step in the activation of the transcription nuclear… Expand
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