CHUK wt Allele

Known as: NFKBIKA, IKK1, Conserved Helix-Loop-Helix Ubiquitous Kinase wt Allele 
Human CHUK wild-type allele is located within 10q24-q25 and is approximately 80 kb in length. This allele, which encodes inhibitor of nuclear factor… Expand
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
  • Geert van Loo, Rossana De Lorenzi, +6 authors Manolis Pasparakis
  • Nature Immunology
  • 2006
Activation of transcription factor NF-κB in the central nervous system (CNS) has been linked to autoimmune demyelinating disease… Expand
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Highly Cited
2003
Highly Cited
2003
The transcription factor NF-kappaB is implicated in various aspects of T cell development and function. The IkappaB kinase (IKK… Expand
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Highly Cited
2003
Highly Cited
2003
Antiapoptotic activity of NF-kappaB in tumors contributes to acquisition of resistance to chemotherapy. Degradation of IkappaB is… Expand
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Highly Cited
2002
Highly Cited
2002
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces apoptosis in a wide range of malignant cells… Expand
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Review
2002
Review
2002
  • J Lin
  • Archives of pharmacal research
  • 2002
The action mechanisms of several chemopreventive agents derived from herbal medicine and edible plants have become attractive… Expand
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2001
2001
IkappaB kinase-1 and IkappaB kinase-2 (IKK1 and IKK2; also called IKKalpha and IKKbeta, respectively) are part of the signal… Expand
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Highly Cited
2000
Highly Cited
2000
We investigated the inhibition of IkappaB kinase (IKK) activity in lipopolysaccharide (LPS)-activated murine macrophages (RAW 264… Expand
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Highly Cited
1999
Highly Cited
1999
Phosphorylation of inhibitor of kappa B (IkappaB) proteins is an important step in the activation of the transcription nuclear… Expand
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Highly Cited
1999
Highly Cited
1999
Phosphorylation of inhibitor of kappa B (IκB) proteins is an important step in the activation of the transcription nuclear factor… Expand
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Highly Cited
1999
Highly Cited
1999
IkappaB kinases (IKKs) IKK1 and IKK2 are two putative IkappaBalpha kinases involved in NF-kappaB activation. To examine the in… Expand
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