conserved helix-loop-helix ubiquitous kinase

Known as: I Kappa B alpha-Associated Protein Kinase, IkappaB Kinase alpha, IKappaB Kinase 
Widely expressed by human CHUK Gene (Ser/Thr IKBK Family), 745-aa 85-kDa Conserved Helix-Loop-Helix Ubiquitous Kinase is an autophosphorylated… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Parkinson's disease (PD) is the second most common neurodegenerative disorder. Despite intense investigations, no effective… (More)
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Highly Cited
2005
Highly Cited
2005
Human mantle cell lymphoma (MCL), an aggressive B cell non-Hodgkin's lymphoma, is characterized by the overexpression of cyclin… (More)
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Highly Cited
2005
Highly Cited
2005
Inflammation and innate immunity involve signalling pathways leading to the production of inflammatory mediators. Usually such… (More)
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Highly Cited
2004
Highly Cited
2004
The two-feedback-loop regulatory module of nuclear factor kappaB (NF-kappaB) signaling pathway is modeled by means of ordinary… (More)
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Highly Cited
2000
Highly Cited
2000
The adapter protein RIP plays a crucial role in NF-kappaB activation by TNF. Here we show that triggering of the p55 TNF receptor… (More)
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Highly Cited
1999
Highly Cited
1999
IkappaB kinases (IKKs) IKK1 and IKK2 are two putative IkappaBalpha kinases involved in NF-kappaB activation. To examine the in… (More)
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Highly Cited
1998
Highly Cited
1998
Activation of the transcription factor NF-kB by inf lammatory cytokines involves the successive action of NF-kB-inducing kinase… (More)
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Highly Cited
1998
Highly Cited
1998
A large protein complex mediates the phosphorylation of the inhibitor of kappaB (IkappaB), which results in the activation of… (More)
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Highly Cited
1997
Highly Cited
1997
tor–associated factor (TRAF) family of adaptor proteins Activation of the transcription factor NF-kB by tumor as signal… (More)
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1995
1995
Helix-loop-helix proteins contain stretches of DNA that encode two amphipathic alpha-helices joined by a loop structure and are… (More)
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