Skip to search formSkip to main contentSkip to account menu

conserved helix-loop-helix ubiquitous kinase

Known as: I Kappa B alpha-Associated Protein Kinase, IkappaB Kinase alpha, IKappaB Kinase 
Widely expressed by human CHUK Gene (Ser/Thr IKBK Family), 745-aa 85-kDa Conserved Helix-Loop-Helix Ubiquitous Kinase is an autophosphorylated… 
National Institutes of Health

Related topics

Related topics

9 relations
CHUK geneCHUK wt AlleleIkappaB kinaseIkappaB kinase activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Phosphorylation of H3 serine 10 by IKKα governs cyclical production of ROS in estrogen-induced transcription and ensures DNA wholeness
Phosphorylation of H3 serine 10 by IKK α governs cyclical production of ROS in estrogen-induced transcription and ensures DNA… 
2012
2012
Network biology approach for identifying key regulatory genes by expression based study of breast cancer
The use of high-throughput array technology is omnipresent in diverse areas specifically, early diagnosis of disease, discovery… 
2011
2011
Mechanisms of the apoptosis induced by CD176 antibody in human leukemic cells.
CD176 (Thomsen-Friedenreich antigen) is a tumor-associated carbohydrate structure. In a previous study, we observed that the anti… 
2006
2006
The PAK1 autoregulatory domain is required for interaction with NIK in Helicobacter pylori-induced NF-κB activation
Abstract Helicobacter pylori, the etiological agent of various human gastric diseases, induces the transcription factor nuclear… 
Highly Cited
2005
Highly Cited
2005
Cyclin D1 Induction through IκB Kinase β/Nuclear Factor-κB Pathway Is Responsible for Arsenite-Induced Increased Cell Cycle G1-S Phase Transition in Human Keratinocytes
Environmental and occupational exposure to arsenite is associated with an increased risk of human cancers, including skin… 
2005
2005
Activation of the IκB kinase complex is sufficient for neuronal differentiation of PC12 cells
We examined the role of the IκB kinase complex in nerve growth factor (NGF)‐induced neuronal differentiation of PC12 cells. We… 
2005
2005
Essential role of IkappaB kinase alpha in the constitutive processing of NF-kappaB2 p100.
Processing of NF-kappaB2 precursor protein p100 to generate p52 is tightly controlled, which is important for proper function of… 
2000
2000
IkappaB kinase alpha is essential for development of the mammalian cornea and conjunctiva.
PURPOSE To determine the requirement of IkappaB kinase alpha (Ikkalpha) for differentiation of the mammalian cornea and… 
1995
1995
CHUK, a conserved helix-loop-helix ubiquitous kinase, maps to human chromosome 10 and mouse chromosome 19.
Helix-loop-helix proteins contain stretches of DNA that encode two amphipathic alpha-helices joined by a loop structure and are… 
1995
1995
CHUK, a new member of the helix-loop-helix and leucine zipper families of interacting proteins, contains a serine-threonine kinase catalytic domain.
We have identified a new member of the helix-loop-helix (H-L-H) and leucine zipper gene families via a reverse transcriptase… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)