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To understand the role of ancestral genomic background in substance dependence (SD) genome-wide association studies (GWAS… Expand Previous findings have demonstrated that variants in nicotinic receptor genes are associated with nicotine, alcohol and cocaine… Expand AIMS
Nicotine dependence is a highly heritable disorder associated with severe medical morbidity and mortality. Recent meta… Expand Numerous genetic linkages, association studies have been performed in different ethnic groups and revealed many susceptibility… Expand The neuronal nicotinic receptor genes (CHRN) have been implicated in a variety of smoking‐related behaviors. Here we tested for… Expand BACKGROUND
Peer smoking provides a socially reinforcing context of friends' encouragement and approval that contributes to… Expand Neuronal nicotinic acetylcholine receptors are activated by both endogenous acetylcholine and exogenous nicotine, making sequence… Expand Neuronal nicotinic acetylcholine receptors have been implicated in various measures of nicotine dependence. In this paper, we… Expand Previous work suggests that young women who smoke cigarettes regularly, or did so in the past, manifest a neurocognitive profile… Expand Despite the health hazards, cigarette smoking is disproportionately frequent among young women. A significant contribution of… Expand