CHRNA5 gene

Known as: CHRNA5, acetylcholine receptor, nicotinic, alpha 5 (neuronal), CHOLINERGIC RECEPTOR, NEURONAL NICOTINIC, ALPHA POLYPEPTIDE 5 
This gene plays a role in ion transport.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Smoking is a leading global cause of disease and mortality. We established the Oxford-GlaxoSmithKline study (Ox-GSK) to perform a… (More)
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Highly Cited
2009
Highly Cited
2009
Alcohol dependence frequently co-occurs with cigarette smoking, another common addictive behavior. Evidence from genetic studies… (More)
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Highly Cited
2009
Highly Cited
2009
Genetic association studies have shown the importance of variants in the CHRNA5-CHRNA3-CHRNB4 cholinergic nicotinic receptor… (More)
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Highly Cited
2009
Highly Cited
2009
Nicotine dependence risk and lung cancer risk are associated with variants in a region of chromosome 15 encompassing genes… (More)
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Highly Cited
2008
Highly Cited
2008
Lung cancer is the most common cause of cancer death worldwide, with over one million cases annually. To identify genetic factors… (More)
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Highly Cited
2008
Highly Cited
2008
To identify risk variants for lung cancer, we conducted a multistage genome-wide association study. In the discovery phase, we… (More)
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE A recent study provisionally identified numerous genetic variants as risk factors for the transition from smoking to… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND A nonsynonymous coding polymorphism, rs16969968, of the CHRNA5 gene that encodes the alpha-5 subunit of the nicotinic… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND One potential site of convergence of the nicotine and alcohol actions is the family of the neuronal nicotinic… (More)
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Highly Cited
2007
Highly Cited
2007
Nicotine dependence is one of the world's leading causes of preventable death. To discover genetic variants that influence risk… (More)
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