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CHRNA5 gene

Known as: CHRNA5, acetylcholine receptor, nicotinic, alpha 5 (neuronal), CHOLINERGIC RECEPTOR, NEURONAL NICOTINIC, ALPHA POLYPEPTIDE 5 
This gene plays a role in ion transport.
National Institutes of Health

Related topics

Related topics

9 relations
CHRNA7 geneCarcinoma of lungHomo sapiensIonophore activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes — A Meta-Analysis
2017
2017
The CHRNA5/CHRNA3/CHRNB4 Nicotinic Receptor Regulome: Genomic Architecture, Regulatory Variants, and Clinical Associations
Functionally related genes often cluster into a genome region under coordinated regulation, forming a local regulome. To… 
2015
2015
CHRNA5 polymorphisms and risk of lung cancer in Chinese Han smokers.
Lung cancer is the most frequent cancer among men in many countries. It is the result of interactions between genetic and… 
Highly Cited
2012
Highly Cited
2012
Impact of human D398N single nucleotide polymorphism on intracellular calcium response mediated by α3β4α5 nicotinic acetylcholine receptors
2012
2012
Subunit composition of α5-containing nicotinic receptors in the rodent habenula
J. Neurochem. (2012) 121, 551–560. 
2012
2012
Circuits, Cells, and Synapses: Toward a New Target for Deep Brain Stimulation in Depression
Understanding the pathophysiology of depression requires knowledge of the anatomical pathways that malfunction in this disorder… 
2011
2011
Combined analysis of CHRNA5, CHRNA3 and CYP2A6 in relation to adolescent smoking behaviour
CYP2A6 influences smoking uptake in adolescence. Genetic variation in the CHRNA5–CHRNA3 region influences smoking behaviour in… 
2011
2011
In Vitro and Ex Vivo Analysis of CHRNA3 and CHRNA5 Haplotype Expression
Genome-wide association studies implicate variations in CHRNA5 and CHRNA3 as being associated with nicotine addiction (NA… 
2011
2011
A Case–Control Study of a Sex-Specific Association between a 15q25 Variant and Lung Cancer Risk
Background: Genetic variants located at 15q25, including those in the cholinergic receptor nicotinic cluster (CHRNA5) have been… 
Highly Cited
2011
Highly Cited
2011
Nicotinic α5 receptor subunit mRNA expression is associated with distant 5′ upstream polymorphisms
CHRNA5, encoding the nicotinic α5 subunit, is implicated in multiple disorders, including nicotine addiction and lung cancer… 
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