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CHFR gene

Known as: CHECKPOINT PROTEIN WITH FHA AND RING FINGER DOMAINS, FLJ10796, CHFR 
This gene is involved in the mitotic checkpoint.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Background: CHFR is a tumor suppressor that arrests the cell cycle at prophase. Results: CHFR regulates the mitotic checkpoint… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND & AIMS Synchronous colorectal neoplasias (2 or more primary carcinomas identified in the same patient) are caused by… Expand
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Highly Cited
2009
Highly Cited
2009
Chfr is a ubiquitin ligase that functions in the mitotic checkpoint by delaying entry into metaphase in response to mitotic… Expand
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Highly Cited
2008
Highly Cited
2008
Background: The CpG island methylator phenotype (CIMP), characterised by widespread promoter methylation, is associated with… Expand
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Highly Cited
2005
Highly Cited
2005
Tumorigenesis is a consequence of loss of tumor suppressors and activation of oncogenes. Expression of the mitotic checkpoint… Expand
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Highly Cited
2005
Highly Cited
2005
Chromosomal instability (CIN) is a cytogenetic hallmark of human cancers. Increasing evidence suggests that impairment of mitotic… Expand
Highly Cited
2003
Highly Cited
2003
Cell-cycle checkpoints controlling the orderly progression through mitosis are frequently disrupted in human cancers. One such… Expand
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Highly Cited
2003
Highly Cited
2003
Mitotic checkpoints prevent errors in chromosome segregation that can lead to neoplasia. Therefore, it is notable that gastric… Expand
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Highly Cited
2003
Highly Cited
2003
Chfr, a mitotic stress checkpoint gene, regulates a prophase delay in cells exposed to agents that disrupt microtubules, such as… Expand
Highly Cited
2001
Highly Cited
2001
We used hierarchical clustering to examine gene expression profiles generated by serial analysis of gene expression (SAGE) in a… Expand
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