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CHFR gene

Known as: CHECKPOINT PROTEIN WITH FHA AND RING FINGER DOMAINS, FLJ10796, CHFR 
This gene is involved in the mitotic checkpoint.
National Institutes of Health

Related topics

Related topics

2 relations
Cell Cycle CheckpointsUbiquitination

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Aggregated Low-Density Lipoprotein Induces LRP1 Stabilization Through E3 Ubiquitin Ligase CHFR Downregulation in Human Vascular Smooth Muscle Cells
Objective—Low density lipoprotein retention and aggregation in the arterial intima are key processes in atherogenesis. Aggregated… 
2013
2013
The Relationship between CHFR mRNA Expression and Clinic-pathological Features in B-cell Non-Hodgkin's Lymphoma
Objective: To investigate the CHFR(checkpoint with FHA and ring finger) expression in non-Hodgkin lymphoma(NHL),and the… 
2010
2010
[Correlation of the methylation status of CpG islands in the promoter region of 10 genes with the 5-Fu chemosensitivity in 3 breast cancer cell lines].
OBJECTIVE To explore the relationship between the methylation status of CpG islands in the promoter region of 10 genes in breast… 
2009
2009
ABCC 8、 CHFR 、 BMP 3 B 、 LOX 、 PRSS 21和 RASSF 1 A 基因启动子的甲基化状态可能与3种乳腺癌细胞株对5-FU的敏感性相关
目的: 寻找与乳腺癌细胞株间药物敏感性差异相关的基因启动子CpG岛甲基化异常,为DNA甲基化异常作为临床化疗敏感性预测手段提供依据。 方法: 用MTT法测定3种乳腺癌细胞株(Bcap-37、T47D和ZR-75-30)对9… 
2008
2008
Deubiquitination of CHFR by USP7HAUSP regulates its stability and activity
2008
2008
Decreased Expression of the Early Mitotic Gene CHFR Contributes to the Acquisition of Breast Cancer Phenotypes
Abstract : CHFR is an E3 ubiquitin ligase that reportedly delays mitosis in response to microtubule-targeting drugs (i.e… 
2007
2007
Analysis of the Checkpoint Protein CHFR-interacting proteins
2006
2006
Aberrant expression of CHFR in malignant peripheral nerve sheath tumors
2004
2004
Epigenetic inactivation of CHFR and sensitivity to microtubule inhibitors in gastric cancer
2004
2004
Μελέτη των γενετικών αλλοιώσεων του ογκοκατασταλτικού γονιδίου CHFR στο μη μικροκυτταρικό καρκίνο του πνεύμανα
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