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CHFR gene

Known as: CHECKPOINT PROTEIN WITH FHA AND RING FINGER DOMAINS, FLJ10796, CHFR 
This gene is involved in the mitotic checkpoint.
National Institutes of Health

Papers overview

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2014
2014
BackgroundGastric carcinoma (GC) has one of the highest mortality rates of cancer diseases and has a high incidence rate in China… Expand
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2013
2013
Protein ubiquitination plays an important role in activating the DNA damage response and maintaining genomic stability. In… Expand
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Highly Cited
2012
Highly Cited
2012
Background: CHFR is a tumor suppressor that arrests the cell cycle at prophase. Results: CHFR regulates the mitotic checkpoint… Expand
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2010
2010
Cellular stress in early mitosis activates the antephase checkpoint, resulting in the decondensation of chromosomes and delayed… Expand
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Highly Cited
2008
Highly Cited
2008
Background: The CpG island methylator phenotype (CIMP), characterised by widespread promoter methylation, is associated with… Expand
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Highly Cited
2005
Highly Cited
2005
Tumorigenesis is a consequence of loss of tumor suppressors and activation of oncogenes. Expression of the mitotic checkpoint… Expand
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2005
2005
Chromosomal instability (CIN) is a cytogenetic hallmark of human cancers. Increasing evidence suggests that impairment of mitotic… Expand
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Highly Cited
2003
Highly Cited
2003
Cell-cycle checkpoints controlling the orderly progression through mitosis are frequently disrupted in human cancers. One such… Expand
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Highly Cited
2003
Highly Cited
2003
Chfr, a mitotic stress checkpoint gene, regulates a prophase delay in cells exposed to agents that disrupt microtubules, such as… Expand
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Highly Cited
2001
Highly Cited
2001
We used hierarchical clustering to examine gene expression profiles generated by serial analysis of gene expression (SAGE) in a… Expand
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