CHFR gene

Known as: CHECKPOINT PROTEIN WITH FHA AND RING FINGER DOMAINS, FLJ10796, CHFR 
This gene is involved in the mitotic checkpoint.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2017
0102020012017

Papers overview

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2011
2011
Protein ubiquitination is a crucial component of the DNA damage response. To study the mechanism of the DNA damage–induced… (More)
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Highly Cited
2005
Highly Cited
2005
Tumorigenesis is a consequence of loss of tumor suppressors and activation of oncogenes. Expression of the mitotic checkpoint… (More)
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2005
2005
We studied the correlations between CHFR (checkpoint with FHA and RING finger) gene methylation and responses to microtubule… (More)
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2005
2005
BACKGROUND/AIMS Recently, aberrant methylation of the CHFR gene associated with gene silencing has been reported in several… (More)
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Highly Cited
2003
Highly Cited
2003
Cell-cycle checkpoints controlling the orderly progression through mitosis are frequently disrupted in human cancers. One such… (More)
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Highly Cited
2003
Highly Cited
2003
Mitotic checkpoints prevent errors in chromosome segregation that can lead to neoplasia. Therefore, it is notable that gastric… (More)
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Highly Cited
2003
Highly Cited
2003
Chfr, a mitotic stress checkpoint gene, regulates a prophase delay in cells exposed to agents that disrupt microtubules, such as… (More)
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2003
2003
We recently described a novel checkpoint pathway that functions early in mitosis to delay chromosome condensation in response to… (More)
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Highly Cited
2002
Highly Cited
2002
The checkpoint protein Chfr delays entry into mitosis, in the presence of mitotic stress (Scolnick, D.M., and T.D. Halazonetis… (More)
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Highly Cited
2002
Highly Cited
2002
The CHFR gene, which was recently cloned by Scolnick and Halazonetis in search for a novel mitotic checkpoint gene with fork-head… (More)
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