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CGS 19755

Known as: CGS-19755 
National Institutes of Health

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Broader (1)

selfotel

Papers overview

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2005
2005
Concurrent locomotor stimulation and decrease in dopamine release in rats and mice after treatment with the competitive NMDA receptor antagonists D-CPPene and CGS 19755
SummaryThe present study was aimed at investigating the effects of the competitive N-methyl-D-aspartate (NMDA) receptor… 
2001
2001
Effects of antagonism of NMDA receptors on transient lower esophageal sphincter relaxations in the dog.
2001
2001
Phencyclidine-induced discriminative stimulus is mediated via phencyclidine binding sites on the N-methyl-d-aspartate receptor-ion channel complex, not via sigma1 receptors
1999
1999
First observations of the safety and tolerability of a competitive antagonist to the glutamate NMDA receptor (CGS 19755) in patients with severe head injury.
A dose escalation, safety, and tolerability study of a competitive antagonist to the N-methyl-D-aspartate (NMDA) glutamate… 
1998
1998
Dose Escalation Safety and Tolerance Study of the Competitive NMDA Antagonist Selfotel (CGS 19755) in Neurosurgery Patients
Selfotel (CGS 19755), a competitivey N-methyl-D-aspartate antagonist, is neuroprotective in experimental models of ischemic… 
1996
1996
Cell swelling exacerbates hypoxic neuronal damage in rat hippocampal slices
1994
1994
Quinolinate-induced injury is enhanced in developing rat brain.
1992
1992
In Vivo Distribution of CGS‐19755 Within Brain in a Model of Focal Cerebral Ischemia
Abstract: The blood–brain barrier permeability of the competitive N‐methyl‐D‐aspartate receptor antagonist CGS‐19755 [cis‐4… 
Highly Cited
1990
Highly Cited
1990
Selective activation of dopaminergic pathways in the mesocortex by compounds that act at the phencyclidine (pcp) binding site: tentative evidence for pcp recognition sites not coupled to n-methyl-d…
Review
1990
Review
1990
CGS 19755: a novel competitive N-methyl-D-aspartate (NMDA) receptor antagonist with anticonvulsant, anxiolytic and anti-ischemic properties.
CGS 19755 is a potent and selective competitive antagonist at NMDA receptors in the brain. In preclinical animal tests, the… 
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