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CGP41251

 
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Vascular smooth muscle (VSM) plays an important role in maintaining vascular tone. In addition to Ca2+-dependent myosin light… Expand
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Highly Cited
2004
Highly Cited
2004
It is well established that oxidative stress is enhanced in diabetes. However, the major in vivo source of oxidative stress is… Expand
Highly Cited
2004
Highly Cited
2004
Resveratrol, a naturally occurring stilbene with antitumor properties, caused mitogen-activated protein kinase [MAPK… Expand
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2002
2002
INTRODUCTION PKC412 (formally CGP41251) selectively inhibits protein kinase C (PKC) isoforms and has been shown to be cytotoxic… Expand
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Review
2001
Review
2001
  • J. Hofmann
  • Reviews of physiology, biochemistry and…
  • 2001
  • Corpus ID: 25362603
PKC isoenzymes were found to be involved in proliferation, antitumor drug resistance and apoptosis. Therefore, it has been tried… Expand
Highly Cited
1999
Highly Cited
1999
Components of cell signaling pathways provide important targets for anticancer drugs. Protein kinase C (PKC) is a serine… Expand
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Review
1998
Review
1998
  • A. Gescher
  • General pharmacology
  • 1998
  • Corpus ID: 20715983
1. Protein kinase C (PKC) is a family of serine/threonine-directed protein kinases that are pivotal regulators of cellular growth… Expand
1996
1996
The antitumor effect of CGP41251 (4'-N-benzoyl staurosporine), a selective protein kinase C (PKC) inhibitor, was examined on two… Expand
Highly Cited
1995
Highly Cited
1995
The intracellular signaling involved in the mechanism of action of zonula occludens toxin (ZOT) was studied using several in… Expand
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Highly Cited
1993
Highly Cited
1993
Stimulation of human neutrophils by the receptor agonist N-formylmethionyl-leucyl-phenylalanine (fMLP) results in a respiratory… Expand
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