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CGP41251

National Institutes of Health

Papers overview

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Review
2003
Review
2003
  • G. Shen
  • Current drug targets. Cardiovascular…
  • 2003
  • Corpus ID: 3162668
Protein kinase C (PKC) represents a family of phospholipid-dependent serine/threonine kinase. PKC was detected in almost all… 
2002
2002
INTRODUCTION PKC412 (formally CGP41251) selectively inhibits protein kinase C (PKC) isoforms and has been shown to be cytotoxic… 
Review
2001
Review
2001
  • J. Hofmann
  • Reviews of physiology, biochemistry and…
  • 2001
  • Corpus ID: 25362603
PKC isoenzymes were found to be involved in proliferation, antitumor drug resistance and apoptosis. Therefore, it has been tried… 
Highly Cited
1999
Highly Cited
1999
Components of cell signaling pathways provide important targets for anticancer drugs. Protein kinase C (PKC) is a serine… 
Review
1998
Review
1998
  • A. Gescher
  • General pharmacology
  • 1998
  • Corpus ID: 20715983
1996
1996
The antitumor effect of CGP41251 (4'-N-benzoyl staurosporine), a selective protein kinase C (PKC) inhibitor, was examined on two… 
Highly Cited
1995
Highly Cited
1995
The intracellular signaling involved in the mechanism of action of zonula occludens toxin (ZOT) was studied using several in… 
Highly Cited
1993
Highly Cited
1993
Stimulation of human neutrophils by the receptor agonist N-formylmethionyl-leucyl-phenylalanine (fMLP) results in a respiratory…