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CGP41251

National Institutes of Health

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PKC412midostaurin

Papers overview

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2006
2006
Antitumor Effect of CGP 41251 , a New Selective Protein Kinase C Inhibitor , on Human Non-Small Cell Lung Cancer Cells
The antitumor effect of CGP41251 (4'-N-benzoyl staurosporine), a selective protein kinase C (PKC) inhibitor, was examined on two… 
2005
2005
Effects of the kinase inhibitor CGP41251 (PKC 412) on lymphocyte activation and TNF-alpha production.
CGP41251 is a serine/threonine and tyrosine kinase inhibitor that is a novel anticancer agent. Because the kinases that CGP41251… 
2004
2004
Evalution of oxidative stress in diabetic animals by in vivo electron spin resonance measurement--role of protein kinase C.
2003
2003
Effects of high glucose on cytokine-induced nerve growth factor (NGF) expression in rat renal mesangial cells.
Review
2001
Review
2001
Modulation of protein kinase C in antitumor treatment.
PKC isoenzymes were found to be involved in proliferation, antitumor drug resistance and apoptosis. Therefore, it has been tried… 
1999
1999
Ectopic expression of protein kinase CbetaII, -delta, and -epsilon, but not -betaI or -zeta, provide for insulin stimulation of glucose uptake in NIH-3T3 cells.
Insulin regulates a diverse array of signaling pathways involved in the control of growth, differentiation, proliferation, and… 
1997
1997
The modulation of multidrug resistance by CGP41251 in B-chronic lymphocytic leukaemia cells in vitro.
1996
1996
Antitumor effect of CGP41251, a new selective protein kinase C inhibitor, on human non-small cell lung cancer cells.
The antitumor effect of CGP41251 (4'-N-benzoyl staurosporine), a selective protein kinase C (PKC) inhibitor, was examined on two… 
1993
1993
A role for protein kinase C-alpha in zymosan-stimulated eicosanoid synthesis in mouse peritoneal macrophages.
A possible regulatory function of protein kinase C (PKC) isoenzymes in zymosan-stimulated eicosanoid synthesis was studied in… 
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