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CGP 6809

Known as: CGP 6'809, CGP-6809 
A water-soluble nitrosourea that cross-links with DNA, causing inhibition of DNA synthesis.
National Institutes of Health

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Nitrosourea Compounds

Papers overview

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2004
2004
Chemotherapeutic studies on N-nitrosoacetoxymethyl-methylamine-and 1,2-dimethylhydrazine-induced colonic tumors in rats: Monotherapy with 5-fluorouracil, ftorafur, CGP 6809, and CGP 15'720A
SummaryColonic tumors were induced in male Sprague-Dawley rats by ten applications of 2 mg/kg/week N-nitrosoacetoxymethyl… 
2004
2004
CGP 6809 — A new nitrosoureido-sugar derivative with activity in human tumor xenografts
SummaryCGP 6809 [ethyl-6-deoxy-3,5-di-O-methyl-6-(3-methyl-3-nitrosoureido)-α-d-glucofuranoside] is a new methylnitrosoureido… 
2004
2004
Phase I trial of a new nitrosourea, CGP 6809, given every 2 weeks
SummaryA phase I study was carried out on a new watersoluble nitrosourea, 6-deoxy-3,5 di-O-methyl 6-(3 methyl-3-nitrosoureido… 
2004
2004
Phase I clinical trial of ethyl 6-deoxy-3,5-di-O-methyl 6-(3 methyl-3-nitrosoureido)-alpha-D-glucofuranoside (CGP 6809)
SummaryA phase I study of single i. v. doses of a new sugar containing nitrosourea 6-deoxy-3,5 di-O-methyl 6-(3 methyl-3… 
2004
2004
CGP 6809, a sugar-containing nitrosourea derivative: pharmacological and physicochemical properties
SummaryCGP 6809 is a water-soluble nitrosourea derivative with quite distinct chemical and biological properties as compared with… 
1985
1985
Therapeutic and diabetogenic potential of two newly synthesized nitrosoureido sugars.
Two newly synthesized nitrosoureido sugars have been evaluated for their antitumor activity and diabetogenic potential in a… 
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