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CGP 6140

Known as: CGP-6140 
National Institutes of Health

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Broader (1)

amocarzine

Papers overview

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2004
2004
In vivo effect of benzothiazole and amoscanate derivatives on the fine structure of adultBrugia spp. andLitomosoides carinii
Alterations in the fine structures of femaleBrugia spp. andLitomosoides carinii were investigated after in vivo treatment with… 
1993
1993
Modulatory effects of antifilarial drugs ivermectin, CGP 6140 and CGP 20376 on the oxidative burst of eosinophilic granulocytes.
1991
1991
Influence of food related to dose on the pharmacokinetics of amocarzine and of its N-oxide metabolite, CGP 13 231, after oral administration to 20 onchocerciasis male patients from Guatemala.
Twenty male patients from Guatemala infected with Onchocerca volvulus received a 3 mg/kg oral dose of amocarzine twice daily for… 
1990
1990
Pharmacokinetics of CGP 6140 (amocarzine) after oral administration of single 100-1600 mg doses to patients with onchocerciasis.
The concentrations of CGP 6140 [4-nitro-4'-(N-methyl-piperazinylthiocarbonylamido)-diphenylamine] and of its N-oxide metabolite… 
1989
1989
Electron microscopic studies on the effects of CGP 6140 and CGP 20376 on microfilariae and third stage larvae of Onchocerca volvulus.
Electron microscopic examination was used to assess the effects of CGP 6140 (proposed generic name: amocarcine) and CGP 20376… 
1989
1989
Studies on the activity of the Ciba Geigy compounds CGP 6140, 20376, 20309 and 21833 against third and fourth stage larvae of Onchocerca volvulus.
The effect of four new antifilarial compounds, (CGP 6140, 20376, 20309 and 21833, Ciba Geigy Ltd. Basle) on the viability of… 
1988
1988
Fully automated analytical system using liquid-solid extraction and liquid chromatography for the determination of CGP 6140 in plasma.
1988
1988
In vitro motility of isolated adults and segments of Onchocerca volvulus, Brugia pahangi and Acanthocheilonema viteae.
Observations were made on the spontaneous motility in vitro of entire adult worms and segments of Onchocerca volvulus, Brugia… 
1987
1987
In vitro study on the effect of the new chemotherapeutic agents CGP 6140 and CGP 20376 on the microfilariae of Onchocerca volvulus.
The effect of two new filaricidal compounds, CGP 6140 and CGP 20376, on the microfilariae of O. volvulus was tested in vitro… 
1987
1987
Effects of the two new anthelmintic agents CGP 6140 and CGP 20376 on adult Paragonimus uterobilateralis in the experimental host Sigmodon hispidus.
The new compounds CGP 6140 and CGP 20376 were tested for their anthelmintic activity against adult Paragonimus uterobilateralis… 
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