amocarzine

Known as: 4-nitro-4'-(N-methyl)piperazinyl thiocarbonylidodiphenylamine, Phenthiourezine, phenithiourezine 
 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

AnthelminticsFilaricidesPiperazines

Narrower (1)

CGP 6140

Papers overview

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2006
2006
Onchocerca parasites and Wolbachia endosymbionts: evaluation of a spectrum of antibiotic types for activity against Onchocerca gutturosa in vitro
BACKGROUND The filarial parasites of major importance in humans contain the symbiotic bacterium Wolbachia and recent studies have… (More)
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1998
1998
Immunoelectron microscopic evidence for release of eosinophil granule matrix protein onto microfilariae of Onchocerca volvulus in the skin after exposure to amocarzine
The involvement of eosinophils in the host reaction to microfilariae (mf) of Onchocerca volvulus was studied by… (More)
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1997
1997
The safety and efficacy of amocarzine in African onchocerciasis and the influence of ivermectin on the clinical and parasitological response to treatment.
The hundred men from a forest area of Ghana, without vector control or ivermectin distribution, were randomized to receive a… (More)
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1996
1996
The economic burden of global blindness: a price too high!
Commentary The economic burden of global blindness: a price too high! The World Health Organisation defines blindness as a best… (More)
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1996
1996
Onchocerciasis in Ecuador: evolution of chorioretinopathy after amocarzine treatment.
AIMS To investigate the impact of the macrofilaricidal drug, amocarzine, on the evolution of chorioretinopathy in onchocerciasis… (More)
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Review
1992
Review
1992
Activity, mechanism of action and pharmacokinetics of 2-tert-butylbenzothiazole and CGP 6140 (amocarzine) antifilarial drugs.
A variety of recently developed drugs, designed to be used in antifilarial chemotherapy, contain a thiocarbonylamide group as a… (More)
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1991
1991
Onchocercacidal effects of amocarzine (CGP 6140) in Latin America
An open clinical trial of amocarzine was carried out in onchocerciasis patients in Ecuador and Guatemala. Administration after… (More)
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1991
1991
Longterm follow-up of onchocerciasis patients in Latin America after treatment and retreatment with amocarzine. Preliminary results.
Amocarzine has been reported to have onchocercacidal effects. Four months posttherapy the majority of adult worms were dead or… (More)
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1991
1991
Use of an ophthalmologic ultrasoundscanner in human onchocercal skin nodules for non-invasive sequential assessment during a macrofilaricidal trial with amocarzine in Guatemala. The first experiences…
Ultrasonography of onchocercal skin nodules was performed with an ophthalmologic real time linear scanner with a B probe of 10… (More)
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1991
1991
Microfilaricidal effect of amocarzine in skin punch biopsies of patients with onchocerciasis from Latin America.
Skin punch biopsies were performed in 54 selected patients with onchocerciasis participating in a clinical trial with amocarzine… (More)
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