Skip to search formSkip to main contentSkip to account menu

amocarzine

Known as: 4-nitro-4'-(N-methyl)piperazinyl thiocarbonylidodiphenylamine, Phenthiourezine, phenithiourezine 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

AnthelminticsFilaricidesPiperazines

Narrower (1)

CGP 6140

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
1997
Review
1997
Research notes from the Onchocerciasis Chemotherapy Research Centre, Ghana.
Brief notes are given on drugs which have been tested at the Onchocerciasis Chemotherapy Research Centre at Tamale and Hohoe and… 
1996
1996
Onchocerciasis in Ecuador: evolution of chorioretinopathy after amocarzine treatment.
AIMS: To investigate the impact of the macrofilaricidal drug, amocarzine, on the evolution of chorioretinopathy in onchocerciasis… 
1996
1996
Polymerase chain reaction-based assessment after macrofilaricidal therapy in Onchocerca volvulus infection.
A recently developed polymerase chain reaction (PCR)-based assay is significantly more sensitive than current methods for… 
1991
1991
Longterm follow-up of onchocerciasis patients in Latin America after treatment and retreatment with amocarzine. Preliminary results.
Amocarzine has been reported to have onchocercacidal effects. Four months posttherapy the majority of adult worms were dead or… 
1991
1991
Onchocercacidal effect of three drug regimens of amocarzine in 148 patients of two races and both sexes from Esmeraldas, Ecuador.
The objective of this multidisciplinary clinical investigation was to test whether amocarzine was absorbed effectively and safely… 
1991
1991
Fine structure of microfilariae in the skin of onchocerciasis patients after exposure to amocarzine.
Transmission electron microscopy was used to demonstrate the effects of amocarzine (CGP 6140) on the fine structure of Onchocerca… 
1991
1991
Microfilaricidal effect of amocarzine in skin punch biopsies of patients with onchocerciasis from Latin America.
Skin punch biopsies were performed in 54 selected patients with onchocerciasis participating in a clinical trial with amocarzine… 
1990
1990
Pharmacokinetics of CGP 6140 (amocarzine) after oral administration of single 100-1600 mg doses to patients with onchocerciasis.
The concentrations of CGP 6140 [4-nitro-4'-(N-methyl-piperazinylthiocarbonylamido)-diphenylamine] and of its N-oxide metabolite… 
1988
1988
[The mouse micronucleus test for mutagenicity of pyronaridine, chloroquine, quinacrine, primaquine, furapyrimidone and phenthiourezine].
1988
1988
[The mouse micronucleus test for mutagenicity of pyronaridine, chloroquine, quinacrine, primaquine, furapyrimidone and phenthiourezine].
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)