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amocarzine
Known as:
4-nitro-4'-(N-methyl)piperazinyl thiocarbonylidodiphenylamine
, Phenthiourezine
, phenithiourezine
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National Institutes of Health
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Related topics
Related topics
4 relations
Broader (3)
Anthelmintics
Filaricides
Piperazines
Narrower (1)
CGP 6140
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Onchocerca parasites and Wolbachia endosymbionts: evaluation of a spectrum of antibiotic types for activity against Onchocerca gutturosa in vitro
S. Townson
,
S. Tagboto
,
Helen F. McGarry
,
G. Egerton
,
M. Taylor
Filaria journal
2006
Corpus ID: 2153163
Background The filarial parasites of major importance in humans contain the symbiotic bacterium Wolbachia and recent studies have…
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2006
2006
Antifilarial activity in vitro of polycarpol and 3-O-acetyl aleuritolic acid from cameroonian medicinal plants against Onchocerca gutturosa
B. Nyassé
,
I. Ngantchou
,
J. Nono
,
B. Schneider
Natural product research
2006
Corpus ID: 6707649
Previous results have revealed the antifilarial activities of crude extracts and pure compounds from some Cameroonian medicinal…
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1998
1998
Immunoelectron microscopic evidence for release of eosinophil granule matrix protein onto microfilariae of Onchocerca volvulus in the skin after exposure to amocarzine
E. J. Gutiérrez-Peña
,
J. Knab
,
D. Büttner
Parasitology Research
1998
Corpus ID: 19745667
Abstract The involvement of eosinophils in the host reaction to microfilariae (mf) of Onchocerca volvulus was studied by…
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1997
1997
The safety and efficacy of amocarzine in African onchocerciasis and the influence of ivermectin on the clinical and parasitological response to treatment.
K. Awadzi
,
N. Opoku
,
+4 authors
N. Kshirsagar
Annals of tropical medicine and parasitology
1997
Corpus ID: 21829577
The hundred men from a forest area of Ghana, without vector control or ivermectin distribution, were randomized to receive a…
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1997
1997
The safety and efficacy of amocarzine in African onchocerciasis and the influence of ivermectin on the clinical and parasitological response to treatment.
K. Awadzi
,
N. Opoku
,
+4 authors
N. Kshirsagar
1997
Corpus ID: 208293083
The hundred men from a forest area of Ghana, without vector control or ivermectin distribution, were randomized to receive a…
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Highly Cited
1996
Highly Cited
1996
The economic burden of global blindness: a price too high!
A. Smith
,
J. Smith
The British journal of ophthalmology
1996
Corpus ID: 34364833
The World Health Organisation defines blindness as a best corrected visual acuity of less than 3/60.1 Using this definition it is…
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1991
1991
Filarial worms: targets for drugs.
C. Ginger
Parasitology today
1991
Corpus ID: 30831717
1991
1991
Use of an ophthalmologic ultrasoundscanner in human onchocercal skin nodules for non-invasive sequential assessment during a macrofilaricidal trial with amocarzine in Guatemala. The first experiences…
A. Poltera
,
O. Reyna
,
G. Zea-Flores
,
F. Beltranena
,
A. Nowell de Arevalo
,
F. Žák
Tropical medicine and parasitology : official…
1991
Corpus ID: 42550039
Ultrasonography of onchocercal skin nodules was performed with an ophthalmologic real time linear scanner with a B probe of 10…
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1991
1991
Amocarzine investigated as oral onchocercacidal drug in 272 adult male patients from Guatemala. Results from three dose regimens spread over three days.
G. Zea-Flores
,
F. Beltranena
,
+7 authors
M. Palomo
Tropical medicine and parasitology : official…
1991
Corpus ID: 569786
The clinical investigations with three types of a three days regimen of amocarzine permitted to adjust the fixed dosing to the…
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1990
1990
The influence of food on the pharmacokinetics of CGP 6140 (amocarzine) after oral administration of a 1200 mg single dose to patients with onchocerciasis.
J. Lecaillon
,
J. Dubois
,
G. Soula
,
E. Pichard
,
A. Poltera
,
C. Ginger
British journal of clinical pharmacology
1990
Corpus ID: 46471795
Eleven male patients from Mali with Onchocerca volvulus infections received in random order a 1200 mg single oral dose of CGP…
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