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CERS5 wt Allele
Known as:
Trh4
, FLJ25304
, Ceramide Synthase 5 wt Allele
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Human CERS5 wild-type allele is located in the vicinity of 12q13.12 and is approximately 38 kb in length. This allele, which encodes ceramide…
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National Institutes of Health
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Related topics
Related topics
2 relations
Apoptosis
Positive Regulation of Apoptosis
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
[Investigating the role of ceramide metabolism-associated CERS5 (LASS5) gene in atherosclerosis pathogenesis in endothelial cells].
N. Coban
,
Filiz Güçlü Geyik
,
Ö. Yildirim
,
Nihan Erginel Ünaltuna
Turk Kardiyoloji Dernegi arsivi : Turk…
2017
Corpus ID: 39952394
OBJECTIVE Ceramide, the backbone of sphingolipids, is the key component affecting atherosclerotic changes through its important…
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2016
2016
LASS5 Interacts with SDHB and Synergistically Represses p53 and p21 Activity.
Z. Jiang
,
F. Li
,
+21 authors
Y. Li
Current molecular medicine
2016
Corpus ID: 6963629
Longevity Assurance 5 (LASS5), a member of the LASS/Ceramide Synthases family, synthesizes C16-ceramide and is implicated in…
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Review
2015
Review
2015
Alternative Antigen Processing for MHC Class I: Multiple Roads Lead to Rome
Cláudia C Oliveira
,
T. van Hall
Front. Immunol.
2015
Corpus ID: 2209418
The well described conventional antigen-processing pathway is accountable for most peptides that end up in MHC class I molecules…
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2011
2011
Peptide transporter TAP mediates between competing antigen sources generating distinct surface MHC class I peptide repertoires
Cláudia C Oliveira
,
Bianca J. Querido
,
M. Sluijter
,
Jens Derbinski
,
S. H. van der Burg
,
T. van Hall
European journal of immunology
2011
Corpus ID: 5283051
We recently described a category of TAP‐independent peptide‐epitopes that are selectively presented by cells with processing…
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2011
2011
D,L-Threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (DL-PDMP) increases endoplasmic reticulum stress, autophagy and apoptosis accompanying ceramide accumulation via ceramide synthase 5 protein…
M. Yamane
,
K. Miyazawa
,
S. Moriya
,
A. Abe
,
S. Yamane
Biochimie
2011
Corpus ID: 23646864
Highly Cited
2006
Highly Cited
2006
Necessary Role for the Lag1p Motif in (Dihydro)ceramide Synthase Activity*
S. Spassieva
,
Jae-gu Seo
,
+5 authors
L. Obeid
Journal of Biological Chemistry
2006
Corpus ID: 31658130
Lag1 (longevity assurance gene 1) homologues, a family of transmembrane proteins found in all eukaryotes, have been shown to be…
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Highly Cited
2005
Highly Cited
2005
Mammalian Lass6 and its related family members regulate synthesis of specific ceramides.
Y. Mizutani
,
A. Kihara
,
Y. Igarashi
The Biochemical journal
2005
Corpus ID: 3191771
The Lass (longevity-assurance homologue) family members, which are highly conserved among eukaryotes, function in ceramide…
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Highly Cited
2005
Highly Cited
2005
LASS5 Is a Bona Fide Dihydroceramide Synthase That Selectively Utilizes Palmitoyl-CoA as Acyl Donor*
S. Lahiri
,
A. Futerman
Journal of Biological Chemistry
2005
Corpus ID: 23941010
We demonstrated recently (Riebeling, C., Allegood, J.C., Wang, E., Merrill, A. H. Jr., and Futerman, A. H. (2003) J. Biol. Chem…
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2005
2005
LASS5 is the predominant ceramide synthase isoform involved in de novo sphingolipid synthesis in lung epithelia Published, JLR Papers in Press, March 16, 2005. DOI 10.1194/jlr.M500001-JLR200
Zhiwei Xu
,
Jiming Zhou
,
D. McCoy
,
R. Mallampalli
Journal of Lipid Research
2005
Corpus ID: 10942790
Ceramide is a key bioactive mediator that inhibits surfactant phosphatidylcholine (PtdCho) synthesis in lung epithelia. Ceramide…
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2005
2005
LASS6, an additional member of the longevity assurance gene family.
A. Weinmann
,
P. Galle
,
A. Teufel
International journal of molecular medicine
2005
Corpus ID: 27318388
Longevity assurance genes (LAGs) represent a subgroup of the homeobox gene family. Five mammalian homologs have been reported…
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