Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

CEROID LIPOFUSCINOSIS, NEURONAL, 2

Known as: CLN2, Ceroid Lipofuscinosis, Neuronal, 2, Variable Age At Onset 
National Institutes of Health

Related topics

Related topics

9 relations
AtaxiaAutosomal recessive inheritanceCerebral atrophyLate-Infantile Neuronal Ceroid Lipfuscinosis
Expand

Broader (1)

Neuronal Ceroid-Lipofuscinoses

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1997
Highly Cited
1997
A role for the Pkc1 MAP kinase pathway of Saccharomyces cerevisiae in bud emergence and identification of a putative upstream regulator
The protein kinase C of Saccharomyces cerevisiae, Pkc1, regulates a MAP kinase, Mpk1, whose activity is stimulated at the G1–S… Expand
Highly Cited
1996
Highly Cited
1996
Rapid Degradation of the G1 Cyclin Cln2 Induced by CDK-Dependent Phosphorylation
Cyclins regulate the major cell cycle transitions in eukaryotes through association with cyclin-dependent protein kinases (CDKs… Expand
Highly Cited
1996
Highly Cited
1996
Cdc53 Targets Phosphorylated G1 Cyclins for Degradation by the Ubiquitin Proteolytic Pathway
In budding yeast, cell division is initiated in late G1 phase once the Cdc28 cyclin-dependent kinase is activated by the G1… Expand
  • figure 1
  • figure 2
  • figure 4
  • figure 5
  • figure 6
Highly Cited
1994
Highly Cited
1994
Collaboration of G1 cyclins in the functional inactivation of the retinoblastoma protein.
The retinoblastoma gene product (pRB) constrains cell proliferation by preventing cell-cycle progression from the G1 to S phase… Expand
Highly Cited
1994
Highly Cited
1994
G1 cyclins CLN1 and CLN2 repress the mating factor response pathway at Start in the yeast cell cycle.
Transcriptional induction by the mating pheromone alpha-factor was monitored at different stages of the yeast cell cycle. G2/M… Expand
Highly Cited
1993
Highly Cited
1993
Properties of Saccharomyces cerevisiae wee1 and its differential regulation of p34CDC28 in response to G1 and G2 cyclins.
Wee1 is a protein kinase that negatively regulates p34cdc2 kinase activity. We have identified a Saccharomyces cerevisiae wee1… Expand
Highly Cited
1993
Highly Cited
1993
Comparison of the Saccharomyces cerevisiae G1 cyclins: Cln3 may be an upstream activator of Cln1, Cln2 and other cyclins.
In the budding yeast Saccharomyces cerevisiae, the G1 cyclins Cln1, Cln2 and Cln3 regulate entry into the cell cycle (Start) by… Expand
Highly Cited
1991
Highly Cited
1991
The role of SWI4 and SWI6 in the activity of G1 cyclins in yeast
Entry into the mitotic cycle (START) requires a protein kinase encoded by the CDC28 gene and one of three redundant G1-specific… Expand
Highly Cited
1991
Highly Cited
1991
Human D-type cyclin
A cDNA library prepared from a human glioblastoma cell line has been introduced into a budding yeast strain that lacks CLN1 and… Expand
Highly Cited
1990
Highly Cited
1990
Identification of a gene necessary for cell cycle arrest by a negative growth factor of yeast: FAR1 is an inhibitor of a G1 cyclin, CLN2
alpha factor is a negative growth factor and differentiation factor that induces G1 arrest and increases transcription of mating… Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE