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CEP 1612

Known as: CEP-1612, CEP1612 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

DipeptidesPhthalimides

Papers overview

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Highly Cited
2001
Highly Cited
2001
CEP1612, a dipeptidyl proteasome inhibitor, induces p21WAF1 and p27KIP1 expression and apoptosis and inhibits the growth of the human lung adenocarcinoma A-549 in nude mice.
The ubiquitin proteasome system is responsible for the proteolysis of important cell cycle and apoptosis-regulatory proteins. In… 
2000
2000
Proteasome inhibitor and lymphocyte function: partial inhibition of cell-mediated cytotoxicity and implication that the lymphocyte proteasome may contain multiple chymotryptic domains.
The multicatalytic proteinase complex or proteasome possesses at least 4 distinct proteolytic activities. We have previously… 
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