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CEBPA gene
Known as:
C/EBP-alpha
, CCAAT/ENHANCER-BINDING PROTEIN, ALPHA
, CEBPA
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This gene plays a role in body weight homeostasis and cellular proliferation. Mutations in the gene are associated with acute myeloid leukemia.
National Institutes of Health
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Related topics
Related topics
13 relations
Acute Myeloid Leukemia with Mutated CEBPA
CCAAT/Enhancer Binding Protein Alpha
CEBPA Gene Mutation
CEBPA gene full mutation analysis:Prid:Pt:Bone mar:Nar:Molgen
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CEBPA wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Acute myeloid leukemia with biallelic CEBPA gene mutations and normal karyotype represents a distinct genetic entity associated with a favorable clinical outcome.
A. Dufour
,
F. Schneider
,
+12 authors
K. Spiekermann
Journal of clinical oncology : official journal…
2010
Corpus ID: 20310446
PURPOSE CEBPA mutations are found as either biallelic (biCEBPA) or monoallelic (moCEBPA). We set out to explore whether the kind…
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Highly Cited
2008
Highly Cited
2008
Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia.
R. Schlenk
,
K. Döhner
,
+11 authors
H. Döhner
The New England journal of medicine
2008
Corpus ID: 2904889
BACKGROUND Mutations occur in several genes in cytogenetically normal acute myeloid leukemia (AML) cells: the nucleophosmin gene…
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Highly Cited
2008
Highly Cited
2008
Prognostic significance of, and gene and microRNA expression signatures associated with, CEBPA mutations in cytogenetically normal acute myeloid leukemia with high-risk molecular features: a Cancer…
G. Marcucci
,
K. Maharry
,
+14 authors
C. Bloomfield
Journal of clinical oncology : official journal…
2008
Corpus ID: 19781541
PURPOSE To evaluate the prognostic significance of CEBPA mutations in the context of established molecular markers in…
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Highly Cited
2005
Highly Cited
2005
Characterization of CEBPA Mutations in Acute Myeloid Leukemia: Most Patients with CEBPA Mutations Have Biallelic Mutations and Show a Distinct Immunophenotype of the Leukemic Cells
L. Lin
,
C. Chen
,
+8 authors
H. Tien
Clinical Cancer Research
2005
Corpus ID: 19463494
Purpose: The transcription factor CCAAT/enhancer binding protein α, encoded by the CEBPA, is crucial for the differentiation of…
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Highly Cited
2004
Highly Cited
2004
CEBPA mutations in younger adults with acute myeloid leukemia and normal cytogenetics: prognostic relevance and analysis of cooperating mutations.
S. Fröhling
,
R. Schlenk
,
+6 authors
K. Döhner
Journal of clinical oncology : official journal…
2004
Corpus ID: 28869571
PURPOSE To assess the prognostic relevance of mutations in the CEBPA gene encoding CCAAT/enhancer binding protein alpha (C/EBP…
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Highly Cited
2003
Highly Cited
2003
Biallelic mutations in the CEBPA gene and low CEBPA expression levels as prognostic markers in intermediate-risk AML.
Sahar Barjesteh van Waalwijk van Doorn-Khosrovani
,
C. Erpelinck
,
+7 authors
R. Delwel
The hematology journal : the official journal of…
2003
Corpus ID: 36743203
The CCAAT/enhancer binding protein alpha is an essential transcription factor for granulocytic differentiation. Recent studies…
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Highly Cited
2003
Highly Cited
2003
Mutations of CEBPA in acute myeloid leukemia FAB types M1 and M2
J. Snaddon
,
M. Smith
,
+7 authors
J. Fitzgibbon
Genes, chromosomes & cancer
2003
Corpus ID: 26592284
CEBPA encodes the transcription factor C/EBPα and is specifically up‐regulated during granulocytic differentiation. The gene is…
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Highly Cited
2002
Highly Cited
2002
Favorable prognostic significance of CEBPA mutations in patients with de novo acute myeloid leukemia: a study from the Acute Leukemia French Association (ALFA).
C. Preudhomme
,
C. Sagot
,
+9 authors
H. Dombret
Blood
2002
Corpus ID: 15382842
The transcription factor C/EBPalpha is crucial for differentiation of mature granulocytes. Recently, different CEBPA gene…
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Highly Cited
2001
Highly Cited
2001
Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia.
T. Pabst
,
B. Mueller
,
+6 authors
D. Tenen
Nature genetics
2001
Corpus ID: 11672781
The transcription factor C/EBPalpha (for CCAAT/enhancer binding protein-alpha; encoded by the gene CEBPA) is crucial for the…
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Highly Cited
1990
Highly Cited
1990
IL-6DBP, a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to CEBP
V. Poli
,
F. Mancini
,
R. Cortese
Cell
1990
Corpus ID: 35411104
We analyzed a family of proteins from hepatoma cell nuclei that bind to interleukin-6 responsive elements (IL-6REs) of several…
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