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CEBPA gene

Known as: C/EBP-alpha, CCAAT/ENHANCER-BINDING PROTEIN, ALPHA, CEBPA 
This gene plays a role in body weight homeostasis and cellular proliferation. Mutations in the gene are associated with acute myeloid leukemia.
National Institutes of Health

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Acute Myeloid Leukemia with Mutated CEBPACCAAT/Enhancer Binding Protein AlphaCEBPA Gene MutationCEBPA gene full mutation analysis:Prid:Pt:Bone mar:Nar:Molgen

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CEBPA wt Allele

Papers overview

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2019
2019
Investigation of CEBPA and CEBPA-AS Genes Expression in Acute Myeloid Leukemia.
Background The pathogenicity of acute myeloid leukemia (AML) is highly influenced by genetic alterations, such as chromosomal… 
2014
2014
Investigation of expression and activity levels of primary rat hepatocyte detoxication genes under various flow rates and cell densities in microfluidic biochips
We investigated the behavior of primary rat hepatocytes in biochips using a microfluidic platform (the integrated dynamic cell… 
2014
2014
The N-terminal CEBPA mutant in acute myeloid leukemia impairs CXCR4 expression
CXC chemokine receptor 4 (CXCR4) is an essential regulator for homing and maintenance of hematopoietic stem cells within the bone… 
2014
2014
Metformin protects the myocardium against isoproterenol-induced injury in rats through alleviating endoplasmic reticulum stress.
Clinical studies have suggested that metformin, a widely used antidiabetic agent, exerts a direct cardioprotective effect on… 
2012
2012
Molecular evaluation of CEBPA gene mutation in normal karyotype acute myeloid leukemia: a comparison of two methods and report of novel CEBPA mutations from Indian acute myeloid leukemia patients.
BACKGROUND AND AIM Mutation in the CAAT/enhancer binding protein-α (CEBPA) gene has been reported as being one of the common… 
2011
2011
Expression of myeloperoxidase and gene mutations in AML patients with normal karyotype: double CEBPA mutations are associated with high percentage of MPO positivity in leukemic blasts
The percentage of myeloperoxidase (MPO)-positive blast cells is a simple and highly significant prognostic factor in AML patients… 
2010
2010
Poor prognosis in familial acute myeloid leukaemia with combined biallelic CEBPA mutations and downstream events affecting the ATM, FLT3 and CDX2 genes
CEBPA is implicated in the delicate balance between myeloid cell proliferation and differentiation. Loss of CEBPA gene function… 
2006
2006
Mutations of the myeloid transcription factor CEBPA are not associated with the blast crisis of chronic myeloid leukaemia
The transcription factor CEBPA is crucial for normal myeloid differentiation. CEBPA gene mutations have been reported in patients… 
Review
2005
Review
2005
Towards a pathogenesis-oriented therapy of acute myeloid leukemia.
2003
2003
Mitogen-responsive expression of RhoB is regulated by RNA stability
The small GTPase-encoding gene RhoB is strongly induced as part of the immediate early response of serum-stimulated fibroblasts… 
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