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CDKN2D protein, human

Known as: INK4D protein, human, p19-INK4d, cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) protein, human 
Cyclin-dependent kinase 4 inhibitor D (166 aa, ~18 kDa) is encoded by the human CDKN2D gene. This protein is involved in both cell cycle regulation… 
National Institutes of Health

Related topics

Related topics

15 relations
Ankyrin RepeatCDKN2D geneCell CycleCell Cycle Control

Broader (1)

Cyclin-Dependent Kinase Inhibitor p19

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Downregulated expression of microRNA‐329 inhibits apoptosis of nigral dopaminergic neurons by regulating CDKN2D expression via the FoxO3a signaling pathway in rats with Parkinson's disease
Parkinson's disease (PD) is a common neurodegenerative disorder due to the loss of dopaminergic neurons in the substantia nigra… 
2017
2017
A c-Myc-regulated stem cell-like signature in high-risk neuroblastoma: A systematic discovery (Target neuroblastoma ESC-like signature)
Abstractc-Myc dysregulation is hypothesized to account for the ‘stemness’ – self-renewal and pluripotency – shared between… 
2015
2015
MiR-451 inhibits proliferation of esophageal carcinoma cell line EC9706 by targeting CDKN2D and MAP3K1.
AIM To investigate the underlying molecular mechanisms of miR-451 to inhibit proliferation of esophageal carcinoma cell line… 
2014
2014
CDKN2D-WDFY2 Is a Cancer-Specific Fusion Gene Recurrent in High-Grade Serous Ovarian Carcinoma
Ovarian cancer is the fifth leading cause of cancer death in women. Almost 70% of ovarian cancer deaths are due to the high-grade… 
2014
2014
Transcriptional repression of CDKN2D by PML/RARα contributes to the altered proliferation and differentiation block of acute promyelocytic leukemia cells
Cell proliferation and differentiation are highly coordinated processes. These two processes are disrupted during leukemogenesis… 
2014
2014
p19-INK4d inhibits neuroblastoma cell growth, induces differentiation and is hypermethylated and downregulated in MYCN-amplified neuroblastomas.
Uncontrolled cell cycle entry, resulting from deregulated CDK-RB1-E2F pathway activity, is a crucial determinant of neuroblastoma… 
2012
2012
A Strategy Based on Protein-Protein Interface Motifs May Help in Identifying Drug Off-Targets
Networks are increasingly used to study the impact of drugs at the systems level. From the algorithmic standpoint, a drug can… 
Highly Cited
2010
Highly Cited
2010
Genomic phenotype of non-cultured pulmonary fibroblasts in idiopathic pulmonary fibrosis.
2007
2007
Expression analysis of PCNA gene in chronic myelogenous leukemia--combined application of siRNA silencing and expression arrays.
Highly Cited
2001
Highly Cited
2001
Increased expression of unmethylated CDKN2D by 5-aza-2′-deoxycytidine in human lung cancer cells
DNA hypermethylation of CpG islands in the promoter region of genes is associated with transcriptional silencing. Treatment with… 
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