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CDC25C wt Allele

Known as: CDC25, Cell Division Cycle 25 Homolog C wt Allele, PPP1R60 
Human CDC25C wild-type allele is located in the vicinity of 5q31 and is approximately 53 kb in length. This allele, which encodes m-phase inducer… 
National Institutes of Health

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Related topics

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Cell Cycle Control

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2000
Highly Cited
2000
Cdc25 inhibition and cell cycle arrest by a synthetic thioalkyl vitamin K analogue.
A synthetic vitamin K analogue, 2-(2-mercaptoethanol)-3-methyl-1,4-naphthoquinone or compound 5 (Cpd 5), was found previously to… 
Highly Cited
1998
Highly Cited
1998
A model of Cdc25 phosphatase catalytic domain and Cdk-interaction surface based on the presence of a rhodanese homology domain.
Mammalian Cdc25 phosphatase is responsible for the dephosphorylation of Cdc2 and other cyclin-dependent kinases at Thr14 and… 
Highly Cited
1998
Highly Cited
1998
MPF amplification in Xenopus oocyte extracts depends on a two-step activation of cdc25 phosphatase.
The activation of Cdc2 kinase induces the entry into M-phase of all eukaryotic cells. We have developed a cell-free system… 
Highly Cited
1997
Highly Cited
1997
A targeted library of small-molecule, tyrosine, and dual-specificity phosphatase inhibitors derived from a rational core design and random side chain variation.
Tyrosine phosphatases (PTPases) dephosphorylate phosphotyrosines while dual-specificity phosphatases (DSPases) dephosphorylate… 
Highly Cited
1993
Highly Cited
1993
Functional analysis of the P box, a domain in cyclin B required for the activation of Cdc25
Review
1992
Review
1992
The cdc25 M-phase inducer: An unconventional protein phosphatase
Highly Cited
1992
Highly Cited
1992
Oscillation of MPF is accompanied by periodic association between cdc25 and cdc2-cyclin B
Highly Cited
1992
Highly Cited
1992
cdc25 is a nuclear protein expressed constitutively throughout the cell cycle in nontransformed mammalian cells
Highly Cited
1991
Highly Cited
1991
The CDC25 protein of Saccharomyces cerevisiae promotes exchange of guanine nucleotides bound to ras
The product of the CDC25 gene of Saccharomyces cerevisiae, in its capacity as an activator of the RAS/cyclic AMP pathway, is… 
Highly Cited
1990
Highly Cited
1990
The C-terminal part of the CDC25 gene product plays a key role in signal transduction in the glucose-induced modulation of cAMP level in Saccharomyces cerevisiae.
In the yeast Saccharomyces cerevisiae, addition of glucose to cells grown under glucose-derepressed conditions induces a… 
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