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CDC25C wt Allele

Known as: CDC25, Cell Division Cycle 25 Homolog C wt Allele, PPP1R60 
Human CDC25C wild-type allele is located in the vicinity of 5q31 and is approximately 53 kb in length. This allele, which encodes m-phase inducer… Expand
National Institutes of Health

Papers overview

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Highly Cited
1999
Highly Cited
1999
DNA damage activates a cell-cycle checkpoint that prevents mitosis while DNA repair is under way. The protein Chk1 enforces this… Expand
Highly Cited
1999
Highly Cited
1999
BACKGROUND In human cells, the mitosis-inducing kinase Cdc2 is inhibited by phosphorylation on Thr14 and Tyr15. Disruption of… Expand
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Highly Cited
1998
Highly Cited
1998
Cdc25 phosphatases activate the cell division kinases throughout the cell cycle. The 2.3 A structure of the human Cdc25A… Expand
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Highly Cited
1995
Highly Cited
1995
The cdc25 phosphatases play key roles in cell cycle progression by activating cyclin-dependent kinases. Two members of the 14-3-3… Expand
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Highly Cited
1992
Highly Cited
1992
The cdc25 protein is a highly specific tyrosine phosphatase that triggers mitosis by dephosphorylating the cdc2 protein kinase… Expand
Highly Cited
1991
Highly Cited
1991
cdc25 controls the activity of the cyclin-p34cdc2 complex by regulating the state of tyrosine phosphorylation of p34cdc2… Expand
Highly Cited
1990
Highly Cited
1990
Entry into mitosis during the somatic cell cycle is regulated in response to signals that monitor the completion of DNA… Expand
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Highly Cited
1990
Highly Cited
1990
Entry into mitosis in fission yeast is controlled by the p34cdc2 protein kinase, which is activated by cdc25+ and inhibited by… Expand
Highly Cited
1987
Highly Cited
1987
The gene corresponding to the S. cerevisiae cell division cycle mutant cdc25 has been cloned and sequenced, revealing an open… Expand
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Highly Cited
1986
Highly Cited
1986
In the fission yeast S. pombe the cdc25+ gene function is required to initiate mitosis. We have cloned the cdc25+ gene and have… Expand