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CDC25C wt Allele

Known as: CDC25, Cell Division Cycle 25 Homolog C wt Allele, PPP1R60 
Human CDC25C wild-type allele is located in the vicinity of 5q31 and is approximately 53 kb in length. This allele, which encodes m-phase inducer… Expand
National Institutes of Health

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Highly Cited
2007
Highly Cited
2007
Movement through the cell cycle is controlled by the temporally and spatially ordered activation of cyclin-dependent kinases… Expand
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Review
2004
Review
2004
The Cdc25 phosphatases function as key regulators of the cell cycle during normal eukaryotic cell division and as mediators of… Expand
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Highly Cited
2002
Highly Cited
2002
Xenopus oocytes, which are arrested in G2 of meiosis I, contain complexes of cyclin B–cdc2 (M phase-promoting factor) that are… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND In human cells, the mitosis-inducing kinase Cdc2 is inhibited by phosphorylation on Thr14 and Tyr15. Disruption of… Expand
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Highly Cited
1993
Highly Cited
1993
The cdc25 phosphatase is a mitotic inducer that activates p34cdc2 at the G2/M transition by dephosphorylation of Tyr15 in p34cdc2… Expand
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Highly Cited
1992
Highly Cited
1992
The cdc25 protein is a highly specific tyrosine phosphatase that triggers mitosis by dephosphorylating the cdc2 protein kinase… Expand
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Highly Cited
1992
Highly Cited
1992
The cdc25 tyrosine phosphatase is known to activate cdc2 kinase in the G2/M transition by dephosphorylation of tyrosine 15. To… Expand
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Highly Cited
1991
Highly Cited
1991
cdc25 controls the activity of the cyclin-p34cdc2 complex by regulating the state of tyrosine phosphorylation of p34cdc2… Expand
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Highly Cited
1990
Highly Cited
1990
Entry into mitosis during the somatic cell cycle is regulated in response to signals that monitor the completion of DNA… Expand
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Highly Cited
1990
Highly Cited
1990
Entry into mitosis in fission yeast is controlled by the p34cdc2 protein kinase, which is activated by cdc25+ and inhibited by… Expand
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