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CDC25C gene

Known as: CELL DIVISION CYCLE 25C, Cell Division Cycle 25 Homolog C Gene, CDC25C 
This gene plays a role in regulation of cell division.
National Institutes of Health

Related topics

Related topics

3 relations
CDC25C protein, humanCdc25C proteinCell Cycle Control

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Calcium store sensor stromal-interaction molecule 1-dependent signaling plays an important role in cervical cancer growth, migration, and angiogenesis
Store-operated Ca2+ entry (SOCE) is the principal Ca2+ entry mechanism in nonexcitable cells. Stromal-interaction molecule 1… 
Highly Cited
2006
Highly Cited
2006
Plumbagin induces G2-M arrest and autophagy by inhibiting the AKT/mammalian target of rapamycin pathway in breast cancer cells
This study is the first to investigate the anticancer effect of plumbagin in human breast cancer cells. Plumbagin exhibited cell… 
Highly Cited
2004
Highly Cited
2004
Sulforaphane-induced G2/M Phase Cell Cycle Arrest Involves Checkpoint Kinase 2-mediated Phosphorylation of Cell Division Cycle 25C*
Previously, we showed that sulforaphane (SFN), a naturally occurring cancer chemopreventive agent, effectively inhibits… 
Highly Cited
2003
Highly Cited
2003
Identification of a Consensus Motif for Plk (Polo-like Kinase) Phosphorylation Reveals Myt1 as a Plk1 Substrate*
Plk1 (Polo-like kinase 1), an evolutionarily conserved serine/threonine kinase, is crucially involved in multiple events during… 
Highly Cited
2000
Highly Cited
2000
The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1.
The investigational anticancer agent 7-hydroxystaurosporine (UCN-01) abrogates the G2 checkpoint in tumor cells and sensitizes… 
Highly Cited
1999
Highly Cited
1999
Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein
DNA damage activates a cell-cycle checkpoint that prevents mitosis while DNA repair is under way. The protein Chk1 enforces this… 
Highly Cited
1997
Highly Cited
1997
Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25.
In response to DNA damage, mammalian cells prevent cell cycle progression through the control of critical cell cycle regulators… 
Highly Cited
1997
Highly Cited
1997
Cdc25 mitotic inducer targeted by chk1 DNA damage checkpoint kinase.
Arrest of the cell cycle at the G2 checkpoint, induced by DNA damage, requires inhibitory phosphorylation of the kinase Cdc2 in… 
Highly Cited
1995
Highly Cited
1995
CDC25 phosphatases as potential human oncogenes.
Cyclin-dependent kinases (CDKs) are activated by CDC25 phosphatases, which remove inhibitory phosphate from tyrosine and… 
Highly Cited
1995
Highly Cited
1995
Cell cycle regulation of the cyclin A, cdc25C and cdc2 genes is based on a common mechanism of transcriptional repression.
The S/G2‐specific transcription of the human cdc25C gene is due to the periodic occupation of a repressor element (‘cell cycle… 
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