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CDC25C gene

Known as: CELL DIVISION CYCLE 25C, Cell Division Cycle 25 Homolog C Gene, CDC25C 
This gene plays a role in regulation of cell division.
National Institutes of Health

Related topics

Related topics

3 relations
CDC25C protein, humanCdc25C proteinCell Cycle Control

Papers overview

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Highly Cited
2008
Highly Cited
2008
CDC25A phosphatase controls meiosis I progression in mouse oocytes.
Highly Cited
2003
Highly Cited
2003
Questioning the Role of Checkpoint Kinase 2 in the p53 DNA Damage Response*
Cdc25C and p53 have been reported to be physiological targets of checkpoint kinase 2 (Chk2). Surprisingly, although Chk2 purified… 
Highly Cited
2002
Highly Cited
2002
Abrogation of the S Phase DNA Damage Checkpoint Results in S Phase Progression or Premature Mitosis Depending on the Concentration of 7-Hydroxystaurosporine and the Kinetics of Cdc25C Activation*
DNA damage causes cell cycle arrest in G1, S, or G2 to prevent replication on damaged DNA or to prevent aberrant mitosis. The G1… 
Highly Cited
2001
Highly Cited
2001
The polo-like kinase Plx1 is required for activation of the phosphatase Cdc25C and cyclin B-Cdc2 in Xenopus oocytes.
In the Xenopus oocyte system mitogen treatment triggers the G(2)/M transition by transiently inhibiting the cAMP-dependent… 
Highly Cited
2000
Highly Cited
2000
Distinct Chk2 Activation Pathways Are Triggered by Genistein and DNA-damaging Agents in Human Melanoma Cells*
Genistein, a natural isoflavone found in soybeans, exerts a number of biological actions suggesting that it may have a role in… 
Highly Cited
1997
Highly Cited
1997
Ultraviolet light-induced G2 phase cell cycle checkpoint blocks cdc25-dependent progression into mitosis
In response to low doses of ultraviolet (U.V.) radiation, cells undergo a G2 delay. In this study we have shown that the G2 delay… 
Highly Cited
1992
Highly Cited
1992
Identification of a mammalian gene structurally and functionally related to the CDC25 gene of Saccharomyces cerevisiae.
The yeast Saccharomyces cerevisiae CDC25 gene encodes a nucleotide-exchange-factor (NEF) that can convert the inactive GDP-bound… 
Highly Cited
1990
Highly Cited
1990
The C-terminal part of the CDC25 gene product plays a key role in signal transduction in the glucose-induced modulation of cAMP level in Saccharomyces cerevisiae.
In the yeast Saccharomyces cerevisiae, addition of glucose to cells grown under glucose-derepressed conditions induces a… 
1988
1988
A new RAS mutation that suppresses the CDC25 gene requirement for growth of Saccharomyces cerevisiae
In the yeast Saccharomyces cerevisiae, the activation of adenylate cyclase requires the products of the RAS genes and of CDC25… 
Highly Cited
1987
Highly Cited
1987
Isolation and nucleotide sequence of a Saccharomyces cerevisiae protein kinase gene suppressing the cell cycle start mutation cdc25.
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