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CDA gene

Known as: CDA, CYTIDINE DEAMINASE, CDD 
This gene is involved in pyrimidine metabolism.
National Institutes of Health

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CDA wt Allele
Cytidine DeaminaseHydrolysis

Papers overview

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Review
2010
Review
2010
Mechanisms of chromosomal rearrangement in the human genome
Many human cancers are associated with characteristic chromosomal rearrangements, especially hematopoietic cancers such as… 
Highly Cited
2009
Highly Cited
2009
Sole copy of Z2‐type human cytidine deaminase APOBEC3H has inhibitory activity against retrotransposons and HIV‐1.
Human cytidine deaminase apolipoprotein B mRNA‐editing catalytic polypeptide‐like 3 (APOBEC3) proteins have been classified as… 
Highly Cited
2008
Highly Cited
2008
Reverse Transcriptase- and RNA Packaging Signal-Dependent Incorporation of APOBEC3G into Hepatitis B Virus Nucleocapsids
ABSTRACT APOBEC3G (A3G) is a cytidine deaminase that can inhibit a wide range of retroviruses, including the para-retrovirus… 
Highly Cited
2007
Highly Cited
2007
Zinc chelation inhibits HIV Vif activity and liberates antiviral function of the cytidine deaminase APOBEC3G
APOBEC3 proteins are cellular antiviral proteins that are targeted for proteasomal degradation by primate lentiviral Vif proteins… 
Highly Cited
2004
Highly Cited
2004
PEG-Ara-C conjugates for controlled release.
Highly Cited
2003
Highly Cited
2003
Human Activation-Induced Cytidine Deaminase Is Induced by IL-4 and Negatively Regulated by CD45: Implication of CD45 as a Janus Kinase Phosphatase in Antibody Diversification 1
Activation-induced cytidine deaminase (AID) plays critical roles in Ig class switch recombination and VH gene somatic… 
Highly Cited
2003
Highly Cited
2003
Msh2 ATPase Activity Is Essential for Somatic Hypermutation at A-T Basepairs and for Efficient Class Switch Recombination
Somatic hypermutation (SHM) and class switch recombination (CSR) are initiated by activation-induced cytidine deaminase–mediated… 
Highly Cited
2002
Highly Cited
2002
Crystal structure of the tetrameric cytidine deaminase from Bacillus subtilis at 2.0 A resolution.
Cytidine deaminases (CDA, EC 3.5.4.5) are zinc-containing enzymes in the pyrimidine salvage pathway that catalyze the formation… 
Highly Cited
1997
Highly Cited
1997
The structure of the cytidine deaminase-product complex provides evidence for efficient proton transfer and ground-state destabilization.
Crystal structures of the cytidine deaminase-uridine product complex prepared either by cocrystallizing enzyme with uridine or by… 
Review
1966
Review
1966
Introduction to the biochemistry of D-arabinosyl nucleosides.
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