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CD94 Antigen

Known as: KLRD1 Protein, Killer Cell Lectin Like Receptor Subfamily D, Member 1, KP43 
Natural killer cells antigen CD94 (179 aa, ~20 kDa) is encoded by the human KLRD1 gene. This protein is involved in signaling in natural killer cells… 
National Institutes of Health

Related topics

Related topics

16 relations
Cytoplasmic DomainHomo sapiensImmunoproteinsIntegral Membrane Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Human CD8+ T cells specific for influenza A virus M1 display broad expression of maturation‐associated phenotypic markers and chemokine receptors
To define the role of memory T cells in a non‐persistent viral infection, we have delineated the phenotype of memory CD8+ T cells… 
Review
2005
Review
2005
Natural killer T cells: rapid responders controlling immunity and disease.
Highly Cited
2002
Highly Cited
2002
NK Cell Receptors of the Orangutan (Pongo pygmaeus): A Pivotal Species for Tracking the Coevolution of Killer Cell Ig-Like Receptors with MHC-C1
CD94, NKG2, Ly49, and killer cell Ig-like receptor (KIR) expressed by orangutan peripheral blood cells were examined by cloning… 
2002
2002
Cutting Edge: CD94/NKG2 Is Expressed on Th1 But Not Th2 Cells and Costimulates Th1 Effector Functions1
Th1 and Th2 cells can be phenotypically distinguished by very few cell surface markers. To identify cell surface molecules that… 
Highly Cited
2001
Highly Cited
2001
Expression of Ly49E and CD94/NKG2 on Fetal and Adult NK Cells1
Murine NK cells express inhibitory receptors belonging to the Ly49 and CD94/NKG2 family. Ly49E and CD94 are the only NK cell… 
Highly Cited
2000
Highly Cited
2000
Crystal structure of human CD69: a C-type lectin-like activation marker of hematopoietic cells.
CD69 is a widely expressed type II transmembrane glycoprotein related to the C-type animal lectins that exhibits regulated… 
Highly Cited
1999
Highly Cited
1999
HLA-E and HLA-G expression on porcine endothelial cells inhibit xenoreactive human NK cells through CD94/NKG2-dependent and -independent pathways.
Human NK cells contribute a significant role to host defense as well as xenogeneic cytotoxicity. Previous studies using human 721… 
Highly Cited
1999
Highly Cited
1999
Cutting edge: expression of functional CD94/NKG2A inhibitory receptors on fetal NK1.1+Ly-49- cells: a possible mechanism of tolerance during NK cell development.
Fetal liver- and thymus-derived NK1.1+ cells do not express known Ly-49 receptors. Despite the absence of Ly-49 inhibitory… 
Highly Cited
1996
Highly Cited
1996
Clonotypic differences in signaling from CD94 (kp43) on NK cells lead to divergent cellular responses.
Ligation of MHC class I-recognizing receptors on NK cells dramatically modulates their secretory and cytotoxic function. This… 
Highly Cited
1996
Highly Cited
1996
Biochemical and serologic evidence for the existence of functionally distinct forms of the CD94 NK cell receptor.
The CD94 NK cell receptor is assembled as a disulfide-linked dimer and appears to be encoded by a single-copy gene of the C-type… 
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