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CD69 wt Allele

Known as: CD69 Molecule wt Allele, CD69, AIM 
Human CD69 wild-type allele is located in the vicinity of 12p13 and is approximately 8 kb in length. This allele, which encodes early activation… 
National Institutes of Health

Related topics

Related topics

5 relations
CD69 antigenLigand BindingReceptor SignalingSignal Transduction

Broader (1)

CD69 gene

Papers overview

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Highly Cited
2007
Highly Cited
2007
Atorvastatin Inhibits T Cell Activation through 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase without Decreasing Cholesterol Synthesis1
The localization of the TCR and other signaling molecules in membrane rafts (MR) is essential for the activation of T lymphocytes… 
Highly Cited
2006
Highly Cited
2006
Depletion of alloreactive T cells via CD69: implications on antiviral, antileukemic and immunoregulatory T lymphocytes
Selective depletion of alloreactive T cells from stem-cell allografts should abrogate graft-versus-host disease while preserving… 
Highly Cited
2002
Highly Cited
2002
Characterization of CD3+CD4-CD8- (double negative) T cells in patients with systemic lupus erythematosus: activation markers
Systemic lupus erythematosus (SLE) is characterized by B cell hyperactivity and the production of autoantibodies, some of which… 
Highly Cited
2002
Highly Cited
2002
Activation markers of human basophils: CD69 expression is strongly and preferentially induced by IL-3.
BACKGROUND The biological functions of basophils are precisely regulated by various cytokines in vitro, but little is known about… 
Highly Cited
2000
Highly Cited
2000
Crystal structure of human CD69: a C-type lectin-like activation marker of hematopoietic cells.
CD69 is a widely expressed type II transmembrane glycoprotein related to the C-type animal lectins that exhibits regulated… 
Highly Cited
1995
Highly Cited
1995
Raf‐1 provides a dominant but not exclusive signal for the induction of CD69 expression on T cells
Stimulation of the T cell antigen receptor (TCR) induces a number of intracellular signaling pathways which lead to the… 
1995
1995
Increased expressions of CD69 and HLA-DR but not of CD25 or CD71 on endometrial T lymphocytes of nonpregnant women.
Highly Cited
1994
Highly Cited
1994
Recombinant CD40 ligand exerts potent biologic effects on T cells.
Murine and human CD40 ligand (CD40L) were recently cloned, expressed, and shown to possess potent activity on human and murine B… 
Highly Cited
1992
Highly Cited
1992
Evidence for early onset, polyclonal activation of T cell subsets in mice homozygous for lpr.
Mice homozygous for lpr and gld develop profound lymphadenopathy characterized by the accumulation of two functionally anergic T… 
1992
1992
CD69, an early activation antigen on lymphocytes, is constitutively expressed by human epidermal Langerhans cells.
When screening skin cryosections with a panel of monoclonal antibodies (MoAb), we found that the anti-CD69 MoAb Leu-23 reacted… 
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