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CD48 antigen

Known as: BCM1 Surface Antigen, Antigen, MRC OX-45, MRC OX 45 Antigen 
A 40-45 KDa GPI-linked protein in the SLAM family that consists of two IMMUNOGLOBULIN C2-SET DOMAINS. It is expressed on the surface of a variety of… 
National Institutes of Health

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CD48 geneIn Bloodagonistsantagonists & inhibitors

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CD48 protein, human

Papers overview

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Review
2006
Review
2006
Of mice and men: different functions of the murine and human 2B4 (CD244) receptor on NK cells.
Highly Cited
2001
Highly Cited
2001
A Molecular Framework for Two-Step T Cell Signaling: Lck Src Homology 3 Mutations Discriminate Distinctly Regulated Lipid Raft Reorganization Events1
Costimulation by CD28 or lipid-raft-associated CD48 potentiate TCR-induced signals, cytoskeletal reorganization, and IL-2… 
Highly Cited
1999
Highly Cited
1999
CD48-deficient mice have a pronounced defect in CD4(+) T cell activation.
We have generated mice deficient in the expression of the lymphocyte cell surface antigen CD48 (Blast-1, BCM1, sgp-60) by gene… 
Highly Cited
1999
Highly Cited
1999
Costs of formal care for frail older people in England: the resource implications study of the MRC cognitive function and ageing study (RIS MRC CFAS).
Highly Cited
1998
Highly Cited
1998
Anti-CD4 monoclonal antibody-induced tolerance to MHC-incompatible cardiac allografts maintained by CD4+ suppressor T cells that are not dependent upon IL-4.
Anti-CD4 mAb-induced tolerance to transplanted tissues has been proposed as due to down-regulation of Thl cells by preferential… 
1996
1996
CD59 and CD48 expressed by rat retinal pigment epithelial cells are major ligands for the CD2-mediated alternative pathway of T cell activation.
The alternative CD2-mediated pathway of T cell activation, which is independent of MHC/peptide recognition by the TCR/CD3 complex… 
Highly Cited
1994
Highly Cited
1994
Flow cytometric measurement of glycosylphosphatidyl-inositol-linked surface proteins on blood cells of patients with paroxysmal nocturnal hemoglobinuria.
Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired disorder of hematopoiesis in which affected cells are deficient in… 
Highly Cited
1993
Highly Cited
1993
The association of the protein tyrosine kinases p56lck and p60fyn with the glycosyl phosphatidylinositol‐anchored proteins Thy‐1 and CD48 in rat thymocytes is dependent on the state of cellular…
Cell surface glycoproteins anchored to the plasma membrane via glycosyl‐phosphatidylinositol (GPI) structures, and hence having… 
Highly Cited
1989
Highly Cited
1989
Cellular basis of allograft rejection in vivo. V. Examination of the mechanisms responsible for the differing efficacy of monoclonal antibody to CD4+ T cell subsets in low- and high-responder rat…
MRC OX35, an anti-CD4 mAb, was used to treat high responder Wistar Furth (W/F) (RT1u) and low responder DA (RT1a) rats which had… 
1976
1976
Autoimmunity and aging: the age-related response of mice of a long-lived strain to trinitrophenylated syngeneic mouse red blood cells.
Mice of 1.5, 9, 22, and 31 to 32 months of age were injected with the thymus-dependent antigen, TNP-SRC, or the thymus… 
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