Skip to search formSkip to main contentSkip to account menu

CD46 protein, human

Known as: TLX, Trophoblast Leukocyte Common Antigen, trophoblast leucocyte common antigen, human 
Membrane cofactor protein (392 aa, ~44 kDa) is encoded by the human CD46 gene. This protein is involved in the classical complementation pathway… 
National Institutes of Health

Related topics

Related topics

13 relations

Broader (2)

CD46 Antigentrophoblast-lymphocyte cross-reactive antigens
CD46 geneCD46 wt AlleleImmunoregulationIntegral Membrane Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
MicroRNA let-7d regulates the TLX/microRNA-9 cascade to control neural cell fate and neurogenesis
MicroRNAs have important functions in the nervous system through post-transcriptional regulation of neurogenesis genes. Here we… 
Review
2009
Review
2009
Clinical testing of engineered oncolytic measles virus strains in the treatment of cancer: an overview.
Viruses have adapted through millennia of evolution to effectively invade and lyse cells through diverse mechanisms. Strains of… 
Highly Cited
2008
Highly Cited
2008
A role for adult TLX-positive neural stem cells in learning and behaviour
Neurogenesis persists in the adult brain and can be regulated by a plethora of external stimuli, such as learning, memory… 
Highly Cited
2008
Highly Cited
2008
The nuclear receptor tailless is required for neurogenesis in the adult subventricular zone.
The tailless (Tlx) gene encodes an orphan nuclear receptor that is expressed by neural stem/progenitor cells in the adult brain… 
Highly Cited
2007
Highly Cited
2007
Orphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation
TLX is a transcription factor that is essential for neural stem cell proliferation and self-renewal. However, the molecular… 
Highly Cited
2001
Highly Cited
2001
Induction of the measles virus receptor SLAM (CD150) on monocytes.
Wild-type strains of measles virus (MV) isolated in B95a cells use the signalling lymphocyte activation molecule (SLAM; also… 
Highly Cited
2000
Highly Cited
2000
The orphan nuclear receptor Tlx regulates Pax2 and is essential for vision.
Although the development of the vertebrate eye is well described, the number of transcription factors known to be key to this… 
Review
2000
Review
2000
Human complement regulators: a major target for pathogenic microorganisms.
Highly Cited
1998
Highly Cited
1998
A Single Amino Acid Change in the Hemagglutinin Protein of Measles Virus Determines Its Ability To Bind CD46 and Reveals Another Receptor on Marmoset B Cells
ABSTRACT This paper provides evidence for a measles virus receptor other than CD46 on transformed marmoset and human B cells. We… 
Highly Cited
1994
Highly Cited
1994
Relationship between Drosophila gap gene tailless and a vertebrate nuclear receptor Tlx
WE report here the identification of a unique vertebrate nuclear receptor, Tlx, which is expressed exclusively in the… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)