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CCNH gene

Known as: CAK complex subunit, CDK-activating kinase complex subunit, cyclin-dependent kinase-activating kinase complex subunit 
This gene plays a role in both basal transcription control and the cell cycle.
National Institutes of Health

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CCNH wt Allele
Cell Cycle ControlDNA RepairHomo sapiensTranscription, Genetic

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2001
2001
MAT1-Modulated CAK Activity Regulates Cell Cycle G1 Exit
ABSTRACT The cyclin-dependent kinase (CDK)-activating kinase (CAK) is involved in cell cycle control, transcription, and DNA… 
Highly Cited
2000
Highly Cited
2000
Interactions of Cdk7 and Kin28 with Hint/PKCI-1 and Hnt1 Histidine Triad Proteins*
Cyclin-dependent kinase 7 (Cdk7) forms a trimeric complex with cyclin H and Mat1 to form the mammalian Cdk-activating kinase, CAK… 
Highly Cited
1998
Highly Cited
1998
Regulation of CAK kinase activity by p53
The growth suppressor p53 is an important key element which controls cell cycle progression in response to cellular stress like… 
Highly Cited
1997
Highly Cited
1997
Inhibition of Eukaryote Protein Kinases by Isoquinoline and Oxazine Alkaloids
O 
1997
1997
Is Cdk7/cyclin H/MAT1 the genuine cdk activating kinase in cycling xenopus egg extracts?
Formation of active cdk (cyclin dependent kinase)/cyclin kinases involves phosphorylation of a conserved threonine residue in the… 
1996
1996
Selective inhibition of cyclic AMP-dependent protein kinase by isoquinoline derivatives.
A large series of isoquinoline derivatives was synthesised including derivatives of isoquinoline, isoquinolino[3,4-c]furazan, 1,2… 
1996
1996
Differential inhibition of eukaryote protein kinases by condensed tannins.
Highly Cited
1994
Highly Cited
1994
The function(s) of CAK, the p34cdc2-activating kinase.
Highly Cited
1993
Highly Cited
1993
Formation of several bacterial c‐type cytochromes requires a novel membrane‐anchored protein that faces the periplasm
We report here the discovery of a novel bacterial gene (cycH) whose product is involved in the biogenesis of most of the cellular… 
1993
1993
Reciprocal regulation of mRNA and protein for subunits of cAMP-dependent protein kinase (RI alpha and C alpha) by cAMP in a neoplastic B cell line (Reh).
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