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CCKBR wt Allele

Known as: Cholecystokinin B Receptor wt Allele, CCK-B Receptor Gene, Gastrin Receptor Gene 
Human CCKBR wild-type allele is located in the vicinity of 11p15.4 and is approximately 12 kb in length. This allele, which encodes gastrin… Expand
National Institutes of Health

Related topics

Related topics

12 relations
11p15.4Cell ProliferationDigestionG Protein-Coupled Receptor Signaling
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
The gastrin and cholecystokinin receptors mediated signaling network: a scaffold for data analysis and new hypotheses on regulatory mechanisms
BackgroundThe gastrointestinal peptide hormones cholecystokinin and gastrin exert their biological functions via cholecystokinin… Expand
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Highly Cited
2014
Highly Cited
2014
CCK2R identifies and regulates gastric antral stem cell states and carcinogenesis
Objective Progastrin is the incompletely cleaved precursor of gastrin that is secreted by G-cells in the gastric antrum. Both… Expand
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2014
2014
Targeting a G-protein-coupled receptor overexpressed in endocrine tumors by magnetic nanoparticles to induce cell death.
Nanotherapy using targeted magnetic nanoparticles grafted with peptidic ligands of receptors overexpressed in cancers is a… Expand
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Highly Cited
2012
Highly Cited
2012
MicroRNA-148b suppresses cell growth by targeting cholecystokinin-2 receptor in colorectal cancer.
MicroRNAs (miRNAs) play an important role in the regulation of a variety of cellular processes, including cell growth… Expand
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2012
2012
Differential sensitivity of types 1 and 2 cholecystokinin receptors to membrane cholesterol
Recent studies indicate that membrane cholesterol can associate with G protein-coupled receptors (GPCRs) and affect their… Expand
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2011
2011
Comparison of the binding and internalization properties of 12 DOTA-coupled and 111In-labelled CCK2/gastrin receptor binding peptides: a collaborative project under COST Action BM0607
PurposeSpecific overexpression of cholecystokinin 2 (CCK2)/gastrin receptors has been demonstrated in several tumours of… Expand
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2009
2009
Signaling through cholesterol esterification: a new pathway for the cholecystokinin 2 receptor involved in cell growth and invasion
Several studies indicate that cholesterol esterification is deregulated in cancers. The present study aimed to characterize the… Expand
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2009
2009
Enhanced targeting with heterobivalent ligands
A novel approach to specifically target tumor cells for detection and treatment is the proposed use of heteromultivalent ligands… Expand
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2007
2007
Involvement of cholecystokinin 2 receptor in food intake regulation: hyperphagia and increased fat deposition in cholecystokinin 2 receptor-deficient mice.
The role of cholecystokinin (CCK) as a satiety factor has been extensively documented. Although most work implies that CCK1… Expand
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2005
2005
A Novel Mechanism for JAK2 Activation by a G Protein-coupled Receptor, the CCK2R
To date very few G protein-coupled receptors (GPCRs) have been shown to be connected to the Janus kinase (JAK)/STAT pathway. Thus… Expand
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