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CCKBR wt Allele

Known as: Cholecystokinin B Receptor wt Allele, CCK-B Receptor Gene, Gastrin Receptor Gene 
Human CCKBR wild-type allele is located in the vicinity of 11p15.4 and is approximately 12 kb in length. This allele, which encodes gastrin… 
National Institutes of Health

Related topics

Related topics

12 relations
11p15.4Cell ProliferationDigestionG Protein-Coupled Receptor Signaling

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Improving the In Vivo Profile of Minigastrin Radiotracers: A Comparative Study Involving the Neutral Endopeptidase Inhibitor Phosphoramidon.
Minigastrin radiotracers, such as [(111)In-DOTA]MG0 ([(111)In-DOTA-DGlu(1)]minigastrin), have been considered for diagnostic… 
Review
2015
Review
2015
Radiolabeled gastrin/CCK analogs in tumor diagnosis: towards higher stability and improved tumor targeting.
Cholecystokinin subtype 2 receptors (CCK2R) are overexpressed in several human cancers, including medullary thyroid carcinoma… 
2012
2012
Somatic Mutations in CCK2R Alter Receptor Activity that Promote Oncogenic Phenotypes
The roles of cholecystokinin 2 receptor (CCK2R) in numerous physiologic processes in the gastrointestinal tract and central… 
Highly Cited
2009
Highly Cited
2009
Enhanced targeting with heterobivalent ligands
A novel approach to specifically target tumor cells for detection and treatment is the proposed use of heteromultivalent ligands… 
2006
2006
Enhanced expression of cholecystokinin‐2 receptor promotes the progression of colon cancer through activation of focal adhesion kinase
Focal adhesion kinase (FAK) is suggested to be intimately involved in the progression of malignancies. Our previous research has… 
2005
2005
Effects of cholecystokinin-receptor antagonists on Fos-like immunoreactivity stimulated by sulfated cholecystokinin-8 in neurons of the myenteric plexus and hindbrain of rats.
OBJECTIVE To evaluate the role of cholecystokinin (CCK)-receptor antagonists in the activation of enteric and hindbrain neurons… 
2002
2002
Genetic, pharmacological and functional analysis of cholecystokinin-1 and cholecystokinin-2 receptor polymorphism in type 2 diabetes and obese patients.
Cholecystokinin (CCK) and gastrin (G) and their receptors (CCK1 and CCK2) are involved in multiple physiological functions… 
Highly Cited
2001
Highly Cited
2001
Cholecystokinin2 receptor-deficient mice display altered function of brain dopaminergic system
Abstract.Rationale: Cholecystokinin (CCK) has been shown to coexist and interact with dopamine in the regulation of behaviour… 
1996
1996
Evaluation of cholecystokinin, gastrin, CCK-A receptor, and CCK-B/gastrin receptor gene expressions in gastric cancer.
1994
1994
Gastrin Receptor Gene Expression in Several Human Carcinomas
Gastrin has been shown to enhance the growth of various human tumors. The present study was designed to examine the gastrin… 
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