FAQ

CCKBR wt Allele

Known as: Cholecystokinin B Receptor wt Allele, CCK-B Receptor Gene, Gastrin Receptor Gene 
Human CCKBR wild-type allele is located in the vicinity of 11p15.4 and is approximately 12 kb in length. This allele, which encodes gastrin… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2017
05101520012017

Related topics

Related topics

12 relations
11p15.4Cell ProliferationDigestionG Protein-Coupled Receptor Signaling
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Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
CCKBR wt Allele
Signal Transduction
Cell Proliferation
Homo sapiens
Digestion
Sensory Process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
MicroRNA-148b suppresses cell growth by targeting cholecystokinin-2 receptor in colorectal cancer.
MicroRNAs (miRNAs) play an important role in the regulation of a variety of cellular processes, including cell growth… (More)
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2012
2012
Differential sensitivity of types 1 and 2 cholecystokinin receptors to membrane cholesterol.
Recent studies indicate that membrane cholesterol can associate with G protein-coupled receptors (GPCRs) and affect their… (More)
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2011
2011
Comparison of the binding and internalization properties of 12 DOTA-coupled and 111In-labelled CCK2/gastrin receptor binding peptides: a collaborative project under COST Action BM0607
Specific overexpression of cholecystokinin 2 (CCK2)/gastrin receptors has been demonstrated in several tumours of neuroendocrine… (More)
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2009
2009
Inactivating cholecystokinin-2 receptor inhibits progastrin-dependent colonic crypt fission, proliferation, and colorectal cancer in mice.
Hyperproliferation of the colonic epithelium, leading to expansion of colonic crypt progenitors, is a recognized risk factor for… (More)
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2009
2009
Signaling through cholesterol esterification: a new pathway for the cholecystokinin 2 receptor involved in cell growth and invasion.
Several studies indicate that cholesterol esterification is deregulated in cancers. The present study aimed to characterize the… (More)
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2008
2008
Regulation of mammalian gastrin/CCK receptor (CCK2R) expression in vitro and in vivo
The gastrin/CCK receptor (CCK2R) mediates the physiological functions of gastrin in the stomach, including stimulation of acid… (More)
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2007
2007
Phosphorylation at Ser244 by CK1 determines nuclear localization and substrate targeting of PKD2.
Protein kinase D2 (PKD2), a member of the PKD family of serine/threonine kinases, is localized in various subcellular… (More)
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2007
2007
Targeting of a CCK2 receptor splice variant with 111In-labelled cholecystokinin-8 (CCK8) and 111In-labelled minigastrin
Radiolabelled cholecystokinin (CCK) and gastrin-derived peptides potentially can be used for peptide receptor radionuclide… (More)
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2006
2006
Enhanced expression of cholecystokinin-2 receptor promotes the progression of colon cancer through activation of focal adhesion kinase.
Focal adhesion kinase (FAK) is suggested to be intimately involved in the progression of malignancies. Our previous research has… (More)
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2005
2005
A novel mechanism for JAK2 activation by a G protein-coupled receptor, the CCK2R: implication of this signaling pathway in pancreatic tumor models.
To date very few G protein-coupled receptors (GPCRs) have been shown to be connected to the Janus kinase (JAK)/STAT pathway. Thus… (More)
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