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CBFA2T3 gene

Known as: MTGR2, RUNX1T3, CBFA2/RUNX1 translocation partner 3 
This gene plays a role in transcriptional regulation.
National Institutes of Health

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CBFA2T3 protein, humanCell Proliferation Regulatory ProcessGranulocyte differentiationTranscriptional Regulation

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CBFA2T3 wt Allele

Papers overview

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2012
2012
Identification of LMO 2 transcriptome and interactome in diffuse large B-cell lymphoma
1Division of Hematology-Oncology, University of Miami, Sylvester Comprehensive Cancer Center, Miami, FL; 2Center for Cancer… 
2009
2009
Eto2/MTG16 and MTGR1 are heteromeric corepressors of the TAL1/SCL transcription factor in murine erythroid progenitors.
2009
2009
Regional expression of MTG genes in the developing mouse central nervous system
Myeloid translocation gene (MTG) proteins are transcriptional repressors that are highly conserved across species. We studied the… 
2007
2007
Expression of AML/Runx and ETO/MTG family members during hematopoietic differentiation of embryonic stem cells.
Highly Cited
2007
Highly Cited
2007
Five distinct biological processes and 14 differentially expressed genes characterize TEL/AML1-positive leukemia
BackgroundThe t(12;21)(p13;q22) translocation is found in 20 to 25% of cases of childhood B-lineage acute lymphoblastic leukemia… 
2005
2005
Myeloid maturation block by AML1-MTG16 is associated with Csf1r epigenetic downregulation
De novo epigenetic changes at histone and DNA level that affect gene transcription in cancer may be less random than we… 
2004
2004
AML1-ETO Decreases ETO-2 (MTG16) Interactions with Nuclear Receptor Corepressor, an Effect That Impairs Granulocyte Differentiation
The t(8;21) chromosome abnormality in acute myeloid leukemia targets the AML1 and ETO genes to produce the leukemia fusion… 
2002
2002
The transcriptional corepressor MTG16a contains a novel nucleolar targeting sequence deranged in t (16; 21)-positive myeloid malignancies
The MTG (Myeloid Translocation Gene) proteins are a family of novel transcriptional corepressors. We report that MTG16a, a… 
2002
2002
A Pediatric Case of Secondary Leukemia Associated with t(16;21)(q24;q22) Exhibiting the Chimeric AML1-MTG16 Gene
A chimeric gene, AML1-MTG16, showing high homology to AML1-MTG8, was recently identified in adult leukemic patients with the… 
1997
1997
Fgfr 2 and osteopontin domains in the developing skull vault are mutually exclusive and can be altered by locally applied FGF 2
S. Iseki1,2, A. O. M. Wilkie3, J. K. Heath4, T. Ishimaru1,2, K. Eto2 and G. M. Morriss-Kay1,* 1Department of Human Anatomy, South… 
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