CB 1954

Known as: CB-1954, CB1954 
 
National Institutes of Health

Papers overview

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2013
2013
BACKGROUND One of the major causes of clinical trial termination is the liver toxicity induced by chemotherapeutic agents… (More)
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Highly Cited
2004
Highly Cited
2004
PURPOSE Virus-directed enzyme prodrug therapy depends on selective delivery of virus encoding a prodrug-activating enzyme to… (More)
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2003
2003
Reactivation of telomerase maintains telomere function and is considered critical to immortalization in most human cancer cells… (More)
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Highly Cited
2001
Highly Cited
2001
To study the function of astrocytes in the adult brain, we have targeted the expression of E. coli nitroreductase (NTR) to the… (More)
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2001
2001
Telomerase activation is considered to be a critical step in cancer progression due to its role in cellular immortalization. The… (More)
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Highly Cited
2000
Highly Cited
2000
A range of luciferase reporter vectors was constructed, incorporating 5'-flanking sequences from the prostate-specific antigen… (More)
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2000
2000
The enzyme nitroreductase from E. coli can reduce the weak, monofunctional alkylating agent 5-(aziridin-1-yl)-2, 4… (More)
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1997
1997
Expression of genes encoding prodrug-activating enzymes can increase the susceptibility of tumor cells to prodrugs, and may… (More)
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1995
1995
A recombinant retrovirus encoding E. coli nitroreductase (NTR) was used to infect mammalian cells. NIH3T3 cells expressing NTR… (More)
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Review
1993
Review
1993
NAD(P)H:Quinone Oxidoreductase1 (NQO1) also known as DT-diaphorase is a flavoprotein that catalyzes the two-electron reduction of… (More)
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