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Antimicrobial Metal Nanomaterials: From Passive to Stimuli‐Activated Applications
This review aims to summarize the currently available research and provide future scope for the development of metal nanomaterial‐based antimicrobial technologies, particularly those that can be activated through externally applied stimuli.
Metal-dependent inhibition of amyloid fibril formation: synergistic effects of cobalt-tannic acid networks.
The geometry of the exposed cobalt coordination site in the cobalt-tannic acid networks facilitates its interactions with histidine and methionine residues in the amyloid beta peptides, and the unique structure of cobalt MPNs may enable a wider variety of biomedical applications.
Mechanism of CB1954 reduction by Escherichia coli nitroreductase.
The reaction mechanism for the reduction of CB1954 by NTR is identified and the nature of the active site of the wild-type enzyme and the preferred binding mode of the substrate are examined.
Modular assembly of superstructures from polyphenol-functionalized building blocks.
This work provides a platform for the rapid generation of superstructured assemblies across a wide range of length scales, from nanometres to centimetres, based on the polyphenol surface-functionalization of micro- and nanoparticles, nanowires, nanosheets, nanocubes and even cells.
Cobalt Phosphate Nanostructures for Non-Enzymatic Glucose Sensing at Physiological pH.
- Pietro Pacchin Tomanin, P. Cherepanov, F. Cavalieri
- Materials Science, ChemistryACS applied materials & interfaces
- 13 November 2018
The synthesis of electrocatalytically active cobalt phosphate nanostructures (CPNs) using a simple, low-cost, and scalable preparation method is reported, suggesting that enhanced detection of Glu by CPNs can be achieved by lowering the surface coordination of cobalt.
Understanding and Designing the Gold-Bio Interface: Insights from Simulations.
A perspective of the current successes and challenges associated with the multiscale computational treatment of Au-bio interfacial systems, from electronic structure calculations to force field methods, is provided to illustrate the links between different approaches and their relationship to experiment and applications.
Identifying the Coiled-Coil Triple Helix Structure of β-Peptide Nanofibers at Atomic Resolution.
These atomic structures of macroscale fibers derived from β3-peptide-based materials provide valuable insight into the effects of the geometric placement of the side chains and the influence of solvent on the core fiber structure which is perpetuated in the superstructure morphology.
Surface-water Interface Induces Conformational Changes Critical for Protein Adsorption: Implications for Monolayer Formation of EAS Hydrophobin
- K. Ley, A. Christofferson, M. Penna, D. Winkler, S. Maclaughlin, I. Yarovsky
- Biology, ChemistryFront. Mol. Biosci.
- 16 November 2015
Results have shown that EAS behaves in a similar way at the air-water and surface-water interfaces, and have highlighted the need for hydrophilic ligand functionalization of the silica surface in order to prevent the adsorption of EAS hydrophobin.
Molecular mapping of poly(methyl methacrylate) super-helix stereocomplexes† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c4sc02971b
The structure of the it-/st-poly(methyl methacrylate) (PMMA) triple-helix stereocomplex is composed of a double helix of it-PMMA of 9 units per turn surrounded by a single helix of st-PMMA with an…
Asymmetric ligand binding in homodimeric Enterobacter cloacae nitroreductase yields the Michaelis complex for nitroaromatic substrates
- A. Christofferson
- Biology, ChemistryJournal of Molecular Modeling
- 17 January 2020
An iterative molecular dynamics simulation protocol provides a rationale for the reduction of p-NBA by NR via a hydride transfer reaction mechanism suggested by experimental results, and brings the proposed reaction mechanism from experiment and computational models into agreement.