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tretazicar

Known as: 5-(1-aziridinyl)-2,4-dinitrobenzamide, 5-aziridinyl-2,4-dinitrobenzamide, aziridine dinitrobenzamide 
A prodrug of a bifunctional alkylating, dinitrobenzamide derivative with antineoplastic activity. Tretazicar can be activated by the human enzyme… 
National Institutes of Health

Papers overview

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2016
2016
The p60 transcription regulator protein (p60TRP) is a basic helix‐loop‐helix (bHLH) domain‐containing neuroprotective protein and… 
2002
2002
A nitroreductase with distinct properties that can activate the prodrug 5-aziridinyl-2,4-dinitrobenzamide (CB 1954) was isolated… 
1972
1972
The selective toxicity of CB 1954 (5‐aziridinyl‐2,4‐dinitrobenzamide) for Walker tumour cells, previously shown in the whole… 
1971
1971
CB 1954, a monofunctional alkylating agent, has exceptional activity against the Walker carcinoma yet is inactive against a large… 
1971
1971
5-Aziridinyl-2,4-Dinitrobenzamide (CB 1954) has been reported to be a highly selective inhibitor of the Walker tumour, with a…