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CAT-354

National Institutes of Health

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Monoclonal Antibodies

Papers overview

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2015
2015
Effect of anti-IL-13 treatment on airway dimensions in severe asthma: Subgroup analysis
Introduction: The effects of the anti-IL-13 monoclonal antibody tralokinumab (tralo) (CAT-354) on airway dimensions were assessed… 
2014
2014
OP011 Tralokinumab (CAT-354), an interleukin 13 antibody, in moderate to severe ulcerative colitis: A phase 2 randomized placebo-controlled study
2014
2014
863 Tralokinumab (CAT-354), an Interleukin 13 Antibody, in Moderate to Severe Ulcerative Colitis: A Phase 2A Randomized Placebo-Controlled Study
2012
2012
Optimization of CAT-354, a therapeutic antibody directed against interleukin-13, using ribosome display.
In this case study, we describe the use of in vitro protein evolution with ribosome display to improve the potency of a human… 
Review
2010
Review
2010
Tralokinumab, an anti-IL-13 mAb for the potential treatment of asthma and COPD.
Biopharmaceutical approaches have been used to target key elements in the processes controlling airway inflammation in asthma and… 
2010
2010
Gateways to clinical trials.
O(6)-Benzylguanine; (-)-Gossypol; Abatacept, AC-2592, Adalimumab, AIDSVAX gp120 B/E, Alemtuzumab, Aliskiren fumarate, ALVAC… 
2010
2010
Investigating The Utility Of Gene-targeted IL-13-humanised Mice To Support Clinical Development Of CAT-354, A Human Specific Therapeutic, For Asthma
2009
2009
Gateways to clinical trials.
(+)-Dapoxetine hydrochloride, [(123)I]-BZA, 9-Aminocamptothecin; Abacavir sulfate/lamivudine, Adalimumab, Adefovir dipivoxil… 
2009
2009
An Open-Label, Parallel-Group, Bioavailability Study To Assess the Pharmacokinetics of CAT-354 Following Subcutaneous and Intravenous Administration in Healthy Subjects.
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