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CAT-152

 
National Institutes of Health

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Highly Cited
2007
Highly Cited
2007
OBJECTIVE To evaluate CAT-152 (lerdelimumab), a monoclonal antibody to transforming growth factor-beta2 (TGF-beta2), in… Expand
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Highly Cited
2006
Highly Cited
2006
PURPOSE Inhibition of TGF-beta reduces myofibroblast differentiation and fibrosis in the cornea. Determining the actions of… Expand
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2006
2006
Transforming growth factor beta (TGFbeta), a potent inducer of cell transdifferentiation, is heavily implicated in fibrotic… Expand
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Highly Cited
2004
Highly Cited
2004
There is increasing evidence implicating Transforming growth factor beta (TGF-beta) in pathological states of the lens. However… Expand
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Highly Cited
2003
Highly Cited
2003
PURPOSE Postoperative subconjunctival wound healing remains the commonest cause of late bleb failure after glaucoma filtration… Expand
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Highly Cited
2002
Highly Cited
2002
PURPOSE To study the role of TGF-beta2 in posterior capsule opacification (PCO) and to determine whether CAT-152 (lerdelimumab… Expand
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Highly Cited
2002
Highly Cited
2002
PURPOSE The human monoclonal antibody that neutralizes the growth factor TGFbeta(2) (CAT-152) safely and effectively inhibits in… Expand
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2002
2002
Norwich, England-A human monoclonal antibody, CAT-152, may help aid bleb survival in patients with primary open-angle glaucoma… Expand
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Highly Cited
2001
Highly Cited
2001
Diabetic nephropathy is characterised by an increase in glomerular and tubular fibrosis that compromises kidney function. The… Expand
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