Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

CAT-152

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
OBJECTIVE To evaluate CAT-152 (lerdelimumab), a monoclonal antibody to transforming growth factor-beta2 (TGF-beta2), in… Expand
Highly Cited
2006
Highly Cited
2006
PURPOSE Inhibition of TGF-beta reduces myofibroblast differentiation and fibrosis in the cornea. Determining the actions of… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Highly Cited
2006
Highly Cited
2006
Transforming growth factor beta (TGFbeta), a potent inducer of cell transdifferentiation, is heavily implicated in fibrotic… Expand
Highly Cited
2004
Highly Cited
2004
There is increasing evidence implicating Transforming growth factor beta (TGF-beta) in pathological states of the lens. However… Expand
Review
2004
Review
2004
Purpose of review This paper summarizes the use of antifibrotic agents adjunctive to glaucoma surgery, reviews recently published… Expand
Highly Cited
2003
Highly Cited
2003
PURPOSE Postoperative subconjunctival wound healing remains the commonest cause of late bleb failure after glaucoma filtration… Expand
  • figure 1
  • table 1
  • figure 2
  • table 2
  • figure 3
Highly Cited
2002
Highly Cited
2002
PURPOSE To study the role of TGF-beta2 in posterior capsule opacification (PCO) and to determine whether CAT-152 (lerdelimumab… Expand
  • figure 1
  • figure 3
  • figure 4
  • figure 5
  • figure 6
Highly Cited
2002
Highly Cited
2002
PURPOSE The human monoclonal antibody that neutralizes the growth factor TGFbeta(2) (CAT-152) safely and effectively inhibits in… Expand
2002
2002
Norwich, England-A human monoclonal antibody, CAT-152, may help aid bleb survival in patients with primary open-angle glaucoma… Expand
Highly Cited
2001
Highly Cited
2001
Diabetic nephropathy is characterised by an increase in glomerular and tubular fibrosis that compromises kidney function. The… Expand
  • table 1
  • figure 1