• Publications
  • Influence
In vitro characterization of a spontaneously immortalized human Müller cell line (MIO-M1).
TLDR
A spontaneously immortalized Müller cell line was characterized that retains the characteristics of primary isolated cells in culture and constitutes the first human Müllers cell line reported in the literature.
Prevalence and clinical characteristics of glaucoma in adult Chinese: a population-based study in Liwan District, Guangzhou.
TLDR
POAG was more common than PACG in this southern Chinese population, with rates similar to those reported in Chinese Singaporeans, indicating that there is a large burden of glaucoma in the Chinese people.
Characterization of the Limbal Epithelial Stem Cell Niche: Novel Imaging Techniques Permit In Vivo Observation and Targeted Biopsy of Limbal Epithelial Stem Cells
TLDR
It is demonstrated how adult stem cell niches can be identified and observed in vivo in humans and new biological insight is provided into the importance of LESC niche structures in maintaining normal L ESC function.
Clinically applicable deep learning for diagnosis and referral in retinal disease
TLDR
A novel deep learning architecture performs device-independent tissue segmentation of clinical 3D retinal images followed by separate diagnostic classification that meets or exceeds human expert clinical diagnoses of retinal disease.
The British Infantile and Childhood Glaucoma (BIG) Eye Study.
TLDR
The British annual incidence of primary congenital glaucoma diagnosis is comparable to that reported for other similar populations and Ethnic minorities from South Asia are at significantly increased risk of PCG.
MIO‐M1 Cells and Similar Müller Glial Cell Lines Derived from Adult Human Retina Exhibit Neural Stem Cell Characteristics
TLDR
Observations indicate that adult human neural retina harbors a population of cells that express both Müller glial and stem cell markers and suggest that these cells may have potential use for cell‐based therapies to restore retinal function.
Expression of vitreous cytokines in proliferative vitreoretinopathy: a prospective study.
TLDR
A model was developed to predict the probability of development of postoperative PVR in patients with rhegmatogenous retinal detachment, and it may be used to indicate intravitreal pharmacologic treatment for those at risk.
Corneal stem cells in review
TLDR
This review will focus on corneal epithelial stem cells in ocular surface repair and regeneration and the current knowledge of stem cell biology in the cornean epithelium, clinical consequences of stemcell deficiency, and therapeutic strategies aimed at reversing stem cell deficiency will be discussed.
...
...